Results 31 to 40 of about 591,098 (317)
A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria [PDF]
, 1994 The novel genetic method of "sheltered RIP" (repeat induced point mutation) was used to generate a Neurospora crassa mutant in which MOM19, a component of the protein import machinery of the mitochondrial outer membrane, can be depleted.
W Neupert +16 more
core +1 more source
Microtubule Integrity Is Associated with the Functional Activity of Mitochondria in HEK293 [PDF]
, 2021 Mitochondria move along the microtubule network and produce bioenergy in the cell. However, there is no report of a relationship between bioenergetic activity of mitochondria and microtubule stability in mammalian cells.
Min Jeong Cho +4 more
core +1 more source
Mitochondria and Neurodegeneration
Bioscience Reports, 2007 Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in mitochondria in various tissues of patients with neurodegenerative disorders, the question “is mitochondrial dysfunction a necessary step in ...
PETROZZI, LUCIA +4 more
openaire +3 more sources
Antioxidants, 2022 Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig +6 more
doaj +1 more source
Mitochondria Associated Germinal Structures in Spermatogenesis: piRNA Pathway Regulation and Beyond [PDF]
, 2020 Multiple specific granular structures are present in the cytoplasm of germ cells, termed nuage, which are electron-dense, non-membranous, close to mitochondria and/or nuclei, variant size yielding to different compartments harboring different components,
Xiaoli Wang +3 more
core +1 more source
Sarcopenia and cardiovascular diseases: A systematic review and meta‐analysis
Journal of Cachexia, Sarcopenia and Muscle, 2023 Sarcopenia is an age‐related disease and is often accompanied by other diseases. Now, many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate of sarcopenia. Therefore, the purpose of this study was to conduct a systematic
Xinrong Zuo +6 more
doaj +1 more source
A new limit for blood metabolite analysis using 1H NMR spectroscopy
Journal of Magnetic Resonance Open, 2022 Human blood is the most widely used biospecimen in the clinic and the metabolomics field. While both mass spectrometry and NMR spectroscopy are the two premier analytical platforms in the metabolomics field, NMR exhibits several unsurpassed ...
G.A. Nagana Gowda +2 more
doaj +1 more source
Protein phosphorylation in yeast mitochondria [PDF]
, 1987 We describe the identification and submitochondrial localization of four protein kinases and of their target proteins in derepressed yeast mitochondria. The activity of one of the kinases depends on the presence of cyclic AMP (cAMP).
Günter Müller +3 more
core +1 more source
Mitochondria Revisited. Alternative Functions of Mitochondria
Bioscience Reports, 1997 This review explores the alternative functions of mitochondria inside the cell. In a general picture of mitochondrial functioning, the importance and uniqueness of these intrinsic functions make them irreplaceable by other intracellular compartments.
D B, Zorov +4 more
openaire +2 more sources
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert +5 more
core +1 more source