Results 11 to 20 of about 589,060 (317)
Journal of Neurology, Neurosurgery & Psychiatry, 2003 Following the discovery in the early 1960s that mitochondria contain their own DNA (mtDNA), there were two major advances, both in the 1980s: the human mtDNA sequence was published in 1981, and in 1988 the first pathogenic mtDNA mutations were identified. The floodgates were opened, and the 1990s became the decade of the mitochondrial genome. There has
P F, Chinnery, E A, Schon
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Journal of Aging Research, 2011 1Division of Biology of Aging, Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32611, USA 2Department of Experimental Medicine, Faculty of Medicine, University of Lleida-IRBLleida, 25008 Lleida, Spain 3Mitochondrial Gerontology and Age-Related Diseases Group, Institute of ...
Leeuwenburgh, Christiaan +2 more
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Mitochondria and Neuroplasticity [PDF]
ASN Neuro, 2010 The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Aiwu Cheng, Yan Hou, Mark P Mattson
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Glutathione and mitochondria [PDF]
Frontiers in Pharmacology, 2014 Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Ribas, Vicent +2 more
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Clinical and Experimental Reproductive Medicine, 2023 In reproduction, mitochondria produce bioenergy, help to synthesize biomolecules, and support the ovaries, oogenesis, and preimplantation embryos, thereby facilitating healthy live births. However, the regulatory mechanism of mitochondria in oocytes and embryos during oogenesis and embryo development has not been clearly elucidated.
Min-Hee Kang, Yu Jin Kim, Jae Ho Lee
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MITOCHONDRIA OF PROTOZOA [PDF]
The Journal of Cell Biology, 1956 A study of thin sections of Paramecium multimicronucleatum, Tetrahymena pyriformis, Tokophrya infusionum, and Amoeba proteus shows that the mitochondria in all these protozoa are similar in certain aspects of their fine structure to that described in metazoan cells.
M A, RUDZINSKA, A W, SEDAR
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Transport of proteins into mitochondria [PDF]
, 1985 Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
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Sarcopenia and peripheral arterial disease: a systematic review
Journal of Cachexia, Sarcopenia and Muscle, 2020 Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia are a population at risk requiring specific and targeted care.
Mégane Pizzimenti +6 more
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Antioxidants, 2023 The aim of this study is to investigate the therapeutic potential of higher doses of PU-91, quercetin, or in combination on transmitochondrial cybrid cell lines with various mtDNA haplogroups derived from patients with age-related macular degeneration ...
Nasim Salimiaghdam +8 more
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Isolation and analysis of fractions enriched in WrappER-associated mitochondria from mouse liver
STAR Protocols, 2021 Summary: The endoplasmic reticulum (ER) plays a central role in lipid homeostasis, but the role of individual ER subdomains in lipid biology has not been elucidated.
Nicolò Ilacqua +2 more
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