Results 251 to 260 of about 240,768 (310)

Parkin-ACSL4 axis in ferroptosis regulation: a narrative review on therapeutic insights from exercise in aging cardiomyocytes. [PDF]

NPJ Metab Health Dis
Kordi N, Bagherzadeh-Rahmani B, KheirAndish R, Rezaali R, Stockwell BR.   +4 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Aberrant Splicing of <i>DNM1L</i> Impairs Cardiac Bioenergetics and Mitochondrial Dynamics in Myotonic Dystrophy Type I (DM1). [PDF]

Circ Genom Precis Med
Adesanya O, Nabie P, Betancourt A, Kalsotra A.   +3 more
europepmc   +1 more source

The importance of mitochondria and mitochondrial calcium signaling in health and disease: an updated outlook on inflammation. [PDF]

J Transl Med
Morciano G, Pellielo G, Agyapong ED, Pellegrino C, Patergnani S, Franceschini D, Koutsikos K, Rigon L, Pinton P, Rimessi A.   +9 more
europepmc   +1 more source

Heart-homed nanomedicine induces fast mitochondrial rescue to enhance cardiac function post-myocardial infarction. [PDF]

Bioact Mater
Qi W, Wang J, Wang S, Shi X, Xiong T, Li R, Zheng W, Liu M, Deng S, Huang Q, Liu J, Ai K.   +11 more
europepmc   +1 more source

Impaired cardiac non-neuronal acetylcholine synthesis triggers mitochondrial dysfunction with the loss of nicotinic receptor-mediated calcium handling, causing the failing heart. [PDF]

Clin Sci (Lond)
Sonobe T, Kai Y, Oikawa S, Akagi T, Mano A, Morita R, Tsuda M, Kakinuma Y.   +7 more
europepmc   +1 more source

On the Feasibility of Clinical Studies with Cross-Linking Mass Spectrometry. [PDF]

J Proteome Res
Park SG, Ostrom EL, Liu S, Marcinek DJ, Bruce JE.   +4 more
europepmc   +1 more source