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A novel transdermal curcumin gel shows potential in improving cardiac bioenergetic functions in Berkeley sickle cell mice. [PDF]
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Science Signaling, 2022
Long-chain fatty acids redirect the uptake of mitochondria released from adipocytes from macrophages to the heart.
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Long-chain fatty acids redirect the uptake of mitochondria released from adipocytes from macrophages to the heart.
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Stobadine and heart mitochondria
Life Sciences, 1999Previous work has shown, that stobadine-hydrochloride (-)cis-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-14-pyrido(4,3b) indole administered in a single dose 2 mg/kg of body weight reduces cardiotoxic effect of isoproterenol (1 mg/kg) as shown by lowered serum enzyme activities of AST, CPK, LDH and ALT.
J, Guzy, E, Barnová, L, Benes
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Current Opinion in Cardiology, 2001
Since the identification of the first pathogenic mutations of mitochondrial DNA in 1988, a plethora of information about human mitochondrial diseases has been brought to light. Not surprisingly, many of these disorders affect the myocardium, because this tissue relies heavily upon oxidative metabolism.
M, Hirano, M, Davidson, S, DiMauro
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Since the identification of the first pathogenic mutations of mitochondrial DNA in 1988, a plethora of information about human mitochondrial diseases has been brought to light. Not surprisingly, many of these disorders affect the myocardium, because this tissue relies heavily upon oxidative metabolism.
M, Hirano, M, Davidson, S, DiMauro
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Rat heart mitochondria release adenosine
Biochemical and Biophysical Research Communications, 1983Isolated rat heart mitochondria release adenosine under specific conditions. Lowest adenosine release occurs at 4 degrees C while highest release occurs in the presence of pyruvate + malate or rotenone at 30 degrees C. The release is attenuated during state 3 respiration, in the presence of atractyloside or in the presence of 1799.
R D, Bukoski, H V, Sparks, L M, Mela
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