Results 31 to 40 of about 240,768 (310)
Localization of TCA cycle dehydrogenases in the mitochondria [PDF]
, 1967 The site of localization of TCA cycle dehydrogenases in mitochondria has been investigated by observing the dehydrogenase activities and fine structure of the fractionated samples after freezing and thawing or sonication of beef heart and rat liver ...
Inaba, Kozo +2 more
core +1 more source
ABCC6 is a basolateral plasma membrane protein [PDF]
, 2013 RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A. +11 more
core +4 more sources
Molecular Perspectives of Mitochondrial Adaptations and Their Role in Cardiac Proteostasis
Frontiers in Physiology, 2020 Mitochondria are the key to properly functioning energy generation in the metabolically demanding cardiomyocytes and thus essential to healthy heart contractility on a beat-to-beat basis.
Shafiul Alam +5 more
doaj +1 more source
The Identification of Prohibitin in the Rat Heart Mitochondria in Heart Failure
Biomedicines, 2021 Mitochondria are considered the main organelles in the cell. They play an important role in both normal and abnormal heart function. There is a supramolecular organization between the complexes of the respiratory chain (supercomplexes (SCs)), which are ...
Yulia Baburina +5 more
doaj +1 more source
Endothelial mitochondria and heart disease [PDF]
Cardiovascular Research, 2010 The endothelium is vital to the proper functioning in the heart, in particular due to its production of nitric oxide (NO) which regulates vascular tone. Damage to the endothelium contributes to the development of atherosclerosis, and hence to possible myocardial infarction and subsequent heart failure.
openaire +2 more sources
Frontiers in Cardiovascular Medicine, 2023 Mitochondria-associated endoplasmic reticulum membranes (MAMs) are formed by physical connections of the endoplasmic reticulum and mitochondria. Over the past decades, great breakthroughs have been made in the study of ER-mitochondria communications.
Yu Zhang +4 more
doaj +1 more source
Carvedilol Protects against Doxorubicin-Induced Mitochondrial Cardiomyopathy [PDF]
, 2002 Several cytopathic mechanisms have been suggested to mediate the dose-limiting cumulative and irreversible cardiomyopathy caused by doxorubicin. Recent evidence indicates that oxidative stress and mitochondrial dysfunction are key factors in the ...
Froberg, M. K. +4 more
core +1 more source
Frontiers in Physiology, 2014 Background and Aims: AIF (apoptosis inducing factor) is a flavin and NADH containing protein located within mitochondria required for optimal function of the respiratory chain.
Qun eChen +5 more
doaj +1 more source
Deficit of female sex hormones desensitizes rat cardiac mitophagy
Chinese Journal of Physiology, 2021 Long-term deprivation of female sex hormones has been shown to mediate accumulation of damaged mitochondria in ventricular muscle leading to cardiovascular dysfunction.
Theerachat Kampaengsri +3 more
doaj +1 more source
Mitochondrial dysfunction in heart diseases: Potential therapeutic effects of Panax ginseng
Frontiers in Pharmacology, 2023 Heart diseases have a high incidence and mortality rate, and seriously affect people’s quality of life. Mitochondria provide energy for the heart to function properly. The process of various heart diseases is closely related to mitochondrial dysfunction.
Xinxin Cao +15 more
doaj +1 more source