Results 21 to 30 of about 1,196,029 (309)

Studies on ferrous ion-induced lipid peroxidation of rat liver mitochondria. I. Effect of inorganic phosphate [PDF]

open access: yes, 1974
Effect of inorganic phosphate on ferrous ion- and ascorbate-induced lipid. peroxidations of isolated rat liver mitochondria was investigated. As a result it has been shown that phosphate accelerates the ferrous ion.induced lipid peroxidation; namely ...
Yamamoto, Goki   +4 more
core   +1 more source

Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]

open access: yes, 1975
Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Oda, Takuzo, Inaba, Kozo
core   +1 more source

Expression of Synj2bp in mouse liver regulates the extent of wrappER-mitochondria contact to maintain hepatic lipid homeostasis

open access: yesBiology Direct, 2022
Background In mouse liver hepatocytes, nearly half of the surface area of every mitochondrion is covered by wrappER, a wrapping-type of ER that is rich in fatty acids and synthesizes lipoproteins (VLDL) (Anastasia et al.
Nicolò Ilacqua   +9 more
doaj   +1 more source

Role of Mitochondria in Alcoholic Liver Disease [PDF]

open access: yesCurrent Pathobiology Reports, 2013
Alcohol-induced liver disease (ALD) is a major health concern of alcohol abuse and a leading cause of liver-related morbidity and mortality. The pathogenesis of ALD is multifactorial and still ill characterized. One of the hallmarks of ALD common for both patients and experimental models is the alteration in the architecture and function of ...
García-Ruiz, Carmen   +2 more
openaire   +3 more sources

Detailed mitochondrial phenotyping by high resolution metabolomics. [PDF]

open access: yesPLoS ONE, 2012
Mitochondrial phenotype is complex and difficult to define at the level of individual cell types. Newer metabolic profiling methods provide information on dozens of metabolic pathways from a relatively small sample.
James R Roede   +4 more
doaj   +1 more source

Increased susceptibility of striatal mitochondria to calcium-induced permeability transition [PDF]

open access: yes, 2003
Mitochondria were simultaneously isolated from striatum and cortex of adult rats and compared in functional assays for their sensitivity to calcium activation of the permeability transition.
Brustovetsky, T   +11 more
core   +1 more source

Mitochondrial Roles and Cytoprotection in Chronic Liver Injury

open access: yesBiochemistry Research International, 2012
The liver is one of the richest organs in terms of number and density of mitochondria. Most chronic liver diseases are associated with the accumulation of damaged mitochondria.
Davide Degli Esposti   +7 more
doaj   +1 more source

Mitochondrial Dysfunction and Chronic Liver Disease

open access: yesCurrent Issues in Molecular Biology, 2022
Mitochondria are generally considered the powerhouse of the cell, a small subcellular organelle that produces most of the cellular energy in the form of adenosine triphosphate (ATP). In addition, mitochondria are involved in various biological functions,
Chunyan Zhang   +5 more
doaj   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

open access: yes, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Walter Neupert   +3 more
core   +1 more source

Regulation of Oxidative Phosphorylation of Liver Mitochondria in Sepsis [PDF]

open access: yes, 2022
The link between liver dysfunction and decreased mitochondrial oxidative phosphorylation in sepsis has been clearly established in experimental models. Energy transduction is plastic: the efficiency of mitochondrial coupling collapses in the early stage ...
Shey-Shing Sheu   +7 more
core   +1 more source

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