Results 21 to 30 of about 178,978 (170)

Inhibitory Effects of Resveratrol against Mitochondrial Toxicity Induced by Perfluorooctanoic Acid in Isolated Liver Mitochondria of Male Rats

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Resveratrol (RSV) is a naturally polyphenolic compound found in grapes and other plant sources. It has potent free radical scavenger and antioxidative properties.The aim of this study was to evaluate the protective effect of ...
Maloos Naderi   +3 more
doaj  

Mitotherapy for Fatty Liver by Intravenous Administration of Exogenous Mitochondria in Male Mice

open access: yesFrontiers in Pharmacology, 2017
Mitochondrial dysfunction is a major and common mechanism in developing non-alcoholic fatty liver disease (NAFLD). Replacement of dysfunctional mitochondria by functional exogenous mitochondria may attenuate intrahepatic excessive lipid and recover ...
Ailing Fu   +3 more
doaj   +1 more source

Potassium Metabolism of Liver Mitochondria.

open access: yesExperimental Biology and Medicine, 1953
SummaryRabbit liver mitochondria contain K which cannot be removed by repeated washings with NaCl solutions at 2°C. This K fraction exchanges with ambient K under appropriate metabolic conditions, indicating a dependence of K metabolism on aerobic oxidation. Orthophosphate depresses the mitochondrial K level.
S W, STANBURY, G H, MUDGE
openaire   +2 more sources

Comparing the Effect of Grape Fermentative Product and Fresh Red Grape Juice on Antioxidant Biomarkers of Liver Mitochondria Isolated From Rats in Vitro

open access: yesResearch in Molecular Medicine, 2021
Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds are used as antioxidant agents. This study aimed to investigate and compare the effects of fresh grape juice red wine on oxidative stress biomarkers in ...
Amir Keshavarzi   +5 more
doaj  

Spermine binding to liver mitochondria

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1996
Non-equilibrium binding of spermine to mitochondrial membranes is studied in rat liver mitochondria by applying a new thermodynamic treatment of ligand-receptor interactions (Di Noto, V., Dalla Via, L., Toninello, A. and Vidali, M. (1996) Macromol. Theory Simul. 5, 165-181).
DALLA VIA, LISA   +3 more
openaire   +3 more sources

Phosphatidylserine biosynthesis in mitochondria from the Morris 7777 hepatoma.

open access: yesJournal of Lipid Research, 1979
Mitochondria from the 7777 hepatoma incorporate substantial amounts of l-[U-(14)C]serine into phospholipid by a Ca(2+)-dependent base-exchange reaction. This reaction is virtually absent in normal liver mitochondria.
K Y Hostetler, B D Zenner, H P Morris
doaj   +1 more source

Peculiarities of the free radical processes in rat liver mitochondria under toxic hepatitis on the background of alimentary protein deficiency [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
The rate of superoxide anion radical, hydroxyl radical and hydrogen peroxide generation, the level of oxidative modification of mitochondrial proteins in the liver of rats with toxic hepatitis was investigated on the background of alimentary protein ...
G. P. Kopylchuk, O. M. Voloshchuk
doaj   +1 more source

The effect of arsenite on rat‐liver mitochondria [PDF]

open access: yesFEBS Letters, 1971
It has been known for some time that arsenite inhibits the oxidation of 2-oxoglutarate by specifically blocking vicinal dithiols of the 2-oxoglutarate dehydrogenase complex [ 1 ] . In liver mitochondria the inhibition is maximal at about 1 mM arsenite [2] .To get complete inhibition it was earlier found essential to preincubate mitochondria with ...
openaire   +2 more sources

Hepatoprotective Effects of Vitamin E Against Malathion-Induced Mitochondrial Dysfunction in Rat Liver

open access: yesAvicenna Journal of Medical Biochemistry, 2014
Background Malathion is an insecticide of the grouping of organophosphate pesticides (OPs), which shows strong insecticidal effects. In addition, vitamin E reacting to cell membrane site may prevent OP-induced oxidative injury.
Ranjbar, Mohsenzadeh, Baeeri
doaj   +1 more source

Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease

open access: yesScientific Reports, 2021
Giant mitochondria are peculiarly shaped, extremely large mitochondria in hepatic parenchymal cells, the internal structure of which is characterised by atypically arranged cristae, enlarged matrix granules and crystalline inclusions.
Gerald J. Shami   +5 more
doaj   +1 more source

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