Results 31 to 40 of about 1,196,029 (309)
Redox Biology, 2018 Mitochondria are critical sources of hydrogen peroxide (H2O2), an important secondary messenger in mammalian cells. Recent work has shown that O2•-/H2O2 emission from individual sites of production in mitochondria is regulated by protein S ...
Julia Chalker +3 more
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Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf-1/ERK1/2/PINK1 Signaling Axis. [PDF]
Adv Sci (Weinh)Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Zhang L +9 more
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Contribution of mitochondria to injury of hepatocytes and liver tissue by hyperthermia
Medicina, 2017 Objective: The aim of this study was to investigate functional changes of liver mitochondria within the experimentally modeled transition zone of radiofrequency ablation and to estimate possible contribution of these changes to the energy status of liver
Rasa Žūkienė +6 more
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Frontiers in Bioengineering and Biotechnology, 2022 The mitochondrion is one of the most important cellular organelles, and many drugs work by acting on mitochondria. Curcumin (Cur)-induced apoptosis of HepG2 in liver cancer cells is closely related to the function of inhibiting mitochondria. However, the
Wanyu Li +7 more
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Effect of pesticides “Butylcaptax (Russia)” and “Droppa (Russia)” on respiration and oxidative phosphorylation of liver mitochondria of pregnant rats and their embryos [PDF]
E3S Web of Conferences, 2021 The article provides information on the effect of pesticides - butylcaptax and droppa on respiration and oxidative phosphorylation of liver mitochondria in rat rats and their embryos.
Alimova Rano +2 more
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Circular DNA's from HeLa cell nuclei and mitochondria [PDF]
, 1970 An electron microscopic observation was made on the DNA's extracted from purified HeLa cell nuclei, mitochondria, and the whole cell, and fractionated by ethidium bromide-cesium chloride density gradient method or sucrose density gradient method. Nuclear
Oda, Takuzo +4 more
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Journal of Mazandaran University of Medical Sciences, 2022 Background and purpose: Resveratrol (RSV) is a naturally polyphenolic compound found in grapes and other plant sources. It has potent free radical scavenger and antioxidative properties.The aim of this study was to evaluate the protective effect of ...
Maloos Naderi +3 more
doaj
Potassium Metabolism of Liver Mitochondria.
Experimental Biology and Medicine, 1953 SummaryRabbit liver mitochondria contain K which cannot be removed by repeated washings with NaCl solutions at 2°C. This K fraction exchanges with ambient K under appropriate metabolic conditions, indicating a dependence of K metabolism on aerobic oxidation. Orthophosphate depresses the mitochondrial K level.
S W, STANBURY, G H, MUDGE
openaire +2 more sources
Mitotherapy for Fatty Liver by Intravenous Administration of Exogenous Mitochondria in Male Mice
Frontiers in Pharmacology, 2017 Mitochondrial dysfunction is a major and common mechanism in developing non-alcoholic fatty liver disease (NAFLD). Replacement of dysfunctional mitochondria by functional exogenous mitochondria may attenuate intrahepatic excessive lipid and recover ...
Ailing Fu +3 more
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Protein phosphorylation in yeast mitochondria [PDF]
, 1987 We describe the identification and submitochondrial localization of four protein kinases and of their target proteins in derepressed yeast mitochondria. The activity of one of the kinases depends on the presence of cyclic AMP (cAMP).
Günter Müller +3 more
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