Results 51 to 60 of about 178,978 (170)

Impact of mitochondrial lipid alterations on liver disease mechanisms and progression

open access: yesExploration of Digestive Diseases
Lipids are intricate biomolecules responsible for the building up of biological membranes. Besides this structural function, they also display crucial roles in signaling, acting as second messengers that activate specific pathways.
Laura Fàbrega   +3 more
doaj   +1 more source

MITOCHONDRIAL CHANGES IN THE KIDNEY AND LIVER OT MICE INDUCED BY OCHRATOXIN A - AN ELECTRONMICROSCOPIC STUDY [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 1994
Ultrastructural changes of renal and hepatic mitochondria in mice induced by OA were studied. Mitrochondria exhibited diverse morphological aberrations. The outer mitochondria) membranes, cristae and matrix were affected. The changes were more prominent
N. Divakaran Nair   +3 more
doaj  

Influence of Essentiale and Succinic acid on liver bioenergetics in experimental Paracetamol intoxication

open access: yesБюллетень сибирской медицины, 2009
The influence of hepatoprotector phospholipid nature Essentiale and Essenciale combination with succinic acid on the metabolism of liver injury caused by Paracetamol in rats has been investigated.
D. A. Korshunov
doaj   +1 more source

Tissue Specific Sensitivity of Mitochondrial Permeability Transition Pore to Ca2+ Ions

open access: yesActa Medica, 2009
Ca2+-induced opening of the mitochondrial permeability transition pore (MPTP) is involved in induction of apoptotic and necrotic processes. We studied sensitivity of MPTP to calcium using the model of Ca2+-induced, cyclosporine A-sensitive mitochondrial ...
René Endlicher   +5 more
doaj   +1 more source

Transport and oxidation of choline by liver mitochondria [PDF]

open access: yesBiochemical Journal, 1977
1. Rapid choline oxidation and the onset of Pi-induced swelling by liver mitochondria, incubated in a sucrose medium at or above pH7.0, required the addition of both Pi and an uncoupling agent. Below pH7.0, Pi alone was required for rapid choline oxidation and swelling. 2.
openaire   +2 more sources

Healthy mitochondria attenuate metabolic dysfunction-associated steatohepatitis by restoring cell metabolism

open access: yesMolecular Biomedicine
Metabolic dysfunction-associated steatohepatitis (MASH) has become a major global health issue. Mitochondrial damage plays a crucial role in the development and progression of MASH.
Peiyu Zhou   +5 more
doaj   +1 more source

Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

open access: yesExperimental and Molecular Medicine, 2019
Liver injury: Citrus peel to the rescue Nobiletin, an antioxidant found in citrus peel, may protect the liver from reperfusion injury, damage following blood flow interruption.
Theodomir Dusabimana   +4 more
doaj   +1 more source

On the Movements of Isolated Liver Mitochondria of the Rat

open access: yesProceedings of the Japanese Histochemical Association, 1960
The movements of mitochondria observed in cells were assumed not only to be passive movements of cytoplasmic currents or Brownian movements, but also to be active as the result of local modifications of surface tension produced by metabolic exchanges. But there have been no reports on the movements of the isolated mitochondria.
openaire   +2 more sources

Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

open access: yesBMC Research Notes, 2010
Background The unbound, free concentration (Bf) of unconjugated bilirubin (UCB), and not the total UCB level, has been shown to correlate with bilirubin cytotoxicity, but the key molecular mechanisms accounting for the toxic effects of UCB are largely ...
Ostrow J Donald   +3 more
doaj   +1 more source

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