Results 271 to 280 of about 1,007,169 (424)

EVIDENCE SUGGESTING THAT THE GRANULES OF MYCOBACTERIA ARE MITOCHONDRIA [PDF]

, 1951
Stuart Mudd, Loren C. Winterscheid, Edward D. DeLamater, Howard J. Henderson   +3 more
openalex   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

Advanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend   +6 more
wiley   +1 more source

Macrophage-derived mitochondria-rich extracellular vesicles aggravate bone loss in periodontitis by disrupting the mitochondrial dynamics of BMSCs. [PDF]

J Nanobiotechnology
Yan J, Yang T, Ma S, Li D, Hu C, Tan J.
europepmc   +1 more source

Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy

Advanced Science, EarlyView.
Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae, Myung‐kyu Choi, Soungyub Ahn, Gwanho Ko, Daniel T. Choe, Hyunsoo Yim, Ken C. Nguyen, Jinseop S. Kim, David H. Hall, Junho Lee   +9 more
wiley   +1 more source

Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns. [PDF]

Invest Ophthalmol Vis Sci
Jiang D, Yu J, Wu X, Yu X, Jin P, Zheng H, Liu H, Xu W, Lian Q, Chen W.   +9 more
europepmc   +1 more source

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

Advanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, Jie Zhang, Shengxi Wu   +11 more
wiley   +1 more source

Engineered mitochondria in diseases: mechanisms, strategies, and applications. [PDF]

Signal Transduct Target Ther
Li M, Wu L, Si H, Wu Y, Liu Y, Zeng Y, Shen B.   +6 more
europepmc   +1 more source

Fat Metabolism in Higher Plants. VII. β-Oxidation of Fatty Acids by Peanut Mitochondria. [PDF]

, 1956
P.K. Stumpf, G.A. Barber
openalex   +1 more source

Synthetic Lethality of SHP2 and XIAP Suppresses Proliferation and Metastasis in KRAS‐mutant Nonsmall Cell Lung Cancer

Advanced Science, EarlyView.
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu, Yu‐wen Sheng, Zhe Fan, Zhao Wu, Ling‐yu Li, Rui‐ying Xi, Xiao‐ke Shi, Guo‐lin Zhang, Fei Wang   +8 more
wiley   +1 more source

Biomineralize Mitochondria in Metal-Organic Frameworks to Promote Mitochondria Transplantation From Non-Tumorigenic Cells Into Cancer Cells. [PDF]

Smart Med
Zhou JN, Liu C, Wang Y, Guo Y, Xu XY, Vuorimaa-Laukkanen E, Koivisto O, Filppula AM, Ye J, Zhang H.   +9 more
europepmc   +1 more source