Results 41 to 50 of about 698,916 (379)
Heat release by isolated mouse brain mitochondria detected with diamond thermometer [PDF]
arXiv, 2022 A production of heat by mitochondria is critical for maintaining body temperature, regulating metabolic rate and preventing oxidative damage to mitochondria and cells. Up to now mitochondrion heat production was characterized only by methods based on fluorescent probes which are sensitive to environmental variations (viscosity, pH, ionic strength ...
arxiv
Mitochondria as a Cellular Hub in Infection and Inflammation
International Journal of Molecular Sciences, 2021 Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as dynamic networks where they adapt energy production based on the cell’s needs. They are also at the center of the proinflammatory response and have essential roles in
P. Andrieux +3 more
semanticscholar +1 more source
The Role of Mitochondria in Oocyte Maturation
Cells, 2021 With the nucleus as an exception, mitochondria are the only animal cell organelles containing their own genetic information, called mitochondrial DNA (mtDNA).
A. Kirillova +3 more
semanticscholar +1 more source
STAMPing into Mitochondria [PDF]
International Journal of Biological Sciences, 2014 Six transmembrane protein of prostate 2 (STAMP2) is a protein that has been extensively studied due to its association with prostate cancer. Currently, STAMP2 is well known for its critical role in metabolism and modulating inflammatory signals. Even so, the molecular mechanism of STAMP2 activity and its downstream effectors are still largely unknown ...
Yoo, SK Yoo, Seong Keun +2 more
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Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes
Stem Cells International, 2017 Human pluripotent stem cells derived cardiomyocytes (PSC-CMs) have been widely used for disease modeling, drug safety screening, and preclinical cell therapy to regenerate myocardium.
Dao-Fu Dai +4 more
doaj +1 more source
Frontiers in Nutrition, 2022 Obesity is a significant health concern as a result of poor-quality diet, for example, high-fat diet (HFD). Although multiple biological and molecular changes have been identified to contribute to HFD-induced pain susceptibility, the mechanisms are not ...
Nan Lian +14 more
doaj +1 more source
Mitochondria and Neurodegeneration
Bioscience Reports, 2007 Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in mitochondria in various tissues of patients with neurodegenerative disorders, the question “is mitochondrial dysfunction a necessary step in ...
PETROZZI, LUCIA +4 more
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Aberrant branched-chain amino acid catabolism in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2022 Globally, cardiovascular diseases are the leading cause of death. Research has focused on the metabolism of carbohydrates, fatty acids, and amino acids to improve the prognosis of cardiovascular diseases.
Yixiao Xiong +5 more
doaj +1 more source
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
PLoS Biology, 2010 Mutations in PINK1 or Parkin lead to familial parkinsonism. The authors suggest that PINK1 and Parkin form a pathway that senses damaged mitochondria and selectively targets them for degradation.
Derek P. Narendra +7 more
semanticscholar +1 more source
Cancers, 2020 Mitochondria are indispensable for energy metabolism and are essential for the regulation of many cellular processes in healthy as well as in transformed cells [...]
openaire +3 more sources