Results 211 to 220 of about 712,444 (333)

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal   +6 more
wiley   +1 more source

Chaperoning mitochondrial biogenesis [PDF]

open access: yes, 1994
Langer, Thomas   +2 more
core  

Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress- LFM images

open access: green
Ehses, Kenneth   +6 more
openalex   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

open access: yesChemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova   +2 more
wiley   +1 more source

PGC-1α: key regulator of mitochondrial biogenesis and cellular differentiation in metabolic and regenerative tissues. [PDF]

open access: yesCell Biosci
Cao L   +9 more
europepmc   +1 more source

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen   +11 more
wiley   +1 more source

Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency. [PDF]

open access: yesProc Natl Acad Sci U S A
Soukar J   +10 more
europepmc   +1 more source

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