Results 31 to 40 of about 186,810 (278)

Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]

, 2016
Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F., Lowes, D. A., McCreath, G., Scullion, M. M. F., Webster, N. R.   +4 more
core   +1 more source

Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes

Marine Drugs, 2014
Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Seung Hun Jeong, Hyoung Kyu Kim, In-Sung Song, Su Jin Noh, Jubert Marquez, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han   +11 more
doaj   +1 more source

Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome

Nature Communications, 2023
Mitochondria contain their own genetic information and a dedicated translation system to express it. The mitochondrial ribosome is assembled from mitochondrial-encoded RNA and nuclear-encoded ribosomal proteins.
Thu Giang Nguyen, Christina Ritter, Eva Kummer   +2 more
doaj   +1 more source

Utilizing small nutrient compounds as enhancers of exercise-induced mitochondrial biogenesis. [PDF]

, 2015
Endurance exercise, when performed regularly as part of a training program, leads to increases in whole-body and skeletal muscle-specific oxidative capacity.
Acheson, Achten, Alemo Munters, Alexander, Andersen, Atherton, Baar, Baggish, Bartlett, Bartlett, Bassett, Beere, Bonen, Bonne, Boon, Bosselaar, Bravo, Bruckbauer, Buijsse, Cantó, Carey, Chen, Chong, Coggan, Crowe, Crowe, Cureton, Cuthbertson, D'Antona, Davis, Davis, Dominy, Dorta, Dulloo, Dulloo, Dumke, Egawa, Egawa, Eid, Fan, Ferketich, Fitts, Ganio, Gibala, Gliemann, Gollnick, Goodyear, Graham, Green, Gualano, Gutiérrez-Salmeán, Hagberg, Harms, Hasler, Hawley, Hawley, Hodgson, Holloszy, Holloszy, Holloszy, Hoppeler, Howitz, Hüttemann, Ingjer, Ivy, Jones, Jung, Kalliokoski, Karlsson, Klausen, Koivisto, Labayen, Lee, Liang, Lin, Little, Lluís, López-Lluch, MacMahon, Martínez-Redondo, Matsakas, Maughan, Merrill, Molé, Montero, Moore, Moore, Morris, Murase, Murase, Murias, Murias, Narkar, Nieman, Nogueira, Olesen, Oscai, Ota, Park, Perez-Schindler, Philp, Pogozelski, Puigserver, Putman, Raben, Randell, Randell, Richter, Sahebkar, Saleem, Saltin, Saltin, Saltin, Saltin, Sawka, Scribbans, Shimotoyodome, Siemann, Simoneau, Smith, Spangenburg, Spina, Spina, Steinberg, Suchankova, Sun, Venables, Wang, White, Winder, Wright, Wright, Yan, Youn, Zhu   +134 more
core   +5 more sources

Mitochondrial biogenesis and turnover [PDF]

Cell Calcium, 2008
Mitochondrial biogenesis is a complex process involving the coordinated expression of mitochondrial and nuclear genes, the import of the products of the latter into the organelle and turnover. The mechanisms associated with these events have been intensively studied in the last 20 years and our understanding of their details is much improved ...
Francisca, Diaz, Carlos T, Moraes
openaire   +2 more sources

Biogenesis of mitochondrial c-type cytochromes [PDF]

, 1990
Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core   +2 more sources

MYC and Mitochondrial Biogenesis [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
Mitochondria, the powerhouses of the cell, face two imperatives concerning biogenesis. The first is the requirement for dividing cells to replicate their mitochondrial content by growth of existing mitochondria. The second is the dynamic regulation of mitochondrial content in response to organismal and cellular cues (e.g., exercise, caloric restriction,
Fionnuala, Morrish, David, Hockenbery
openaire   +2 more sources

Biogenesis of Mitochondrial Metabolite Carriers [PDF]

Biomolecules, 2020
Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers have to be imported into mitochondria from the cytosol.
Patrick Horten, Lilia Colina-Tenorio, Heike Rampelt   +2 more
openaire   +4 more sources

Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

Adipocyte, 2022
Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes (T2DM). Decreased mitochondrial abundance and function were found in white adipose tissue (WAT) of T2DM patients.
Jialin Sun, Ping Leng, Xiao Li, Qie Guo, Jun Zhao, Yu Liang, Xiaolei Zhang, Xue Yang, Jing Li   +8 more
doaj   +1 more source

Upregulation of Mitochondrial Content in Cytochrome c Oxidase Deficient Fibroblasts. [PDF]

PLoS ONE, 2016
Cytochrome-c-oxidase (COX) deficiency is a frequent cause of mitochondrial disease and is associated with a wide spectrum of clinical phenotypes. We studied mitochondrial function and biogenesis in fibroblasts derived from the Cohen (CDs) rat, an animal ...
Aviram Kogot-Levin, Ann Saada, Gil Leibowitz, Devorah Soiferman, Liza Douiev, Itamar Raz, Sarah Weksler-Zangen   +6 more
doaj   +1 more source