Results 31 to 40 of about 712,444 (333)
In situ observation of mitochondrial biogenesis as the early event of apoptosis
iScience, 2021 Summary: Mitochondrial biogenesis is a cell response to external stimuli which is generally believed to suppress apoptosis. However, during the process of apoptosis, whether mitochondrial biogenesis occurs in the early stage of the apoptotic cells ...
Chang-Sheng Shao +5 more
doaj +1 more source
Selenite stimulates mitochondrial biogenesis signaling and enhances mitochondrial functional performance in murine hippocampal neuronal cells. [PDF]
PLoS ONE, 2012 Supplementation of selenium has been shown to protect cells against free radical mediated cell damage. The objectives of this study are to examine whether supplementation of selenium stimulates mitochondrial biogenesis signaling pathways and whether ...
Natalia Mendelev +4 more
doaj +1 more source
Quercetin Increases Mitochondrial Biogenesis and Reduces Free Radicals in Neuronal SH-SY5Y Cells
Nutrients, 2022 Alzheimer’s disease (AD) is a common neurodegenerative disorder that causes dementia and affects millions of people worldwide. The mechanism underlying AD is unclear; however, oxidative stress and mitochondrial biogenesis have been reported to be ...
Chia-ling Ho +4 more
semanticscholar +1 more source
Nature Communications, 2022 Parkin, an E3 ubiquitin ligase, plays an essential role in mitochondrial quality control. However, the mechanisms by which Parkin connects mitochondrial homeostasis with cellular metabolism in adipose tissue remain unclear.
T. Moore +16 more
semanticscholar +1 more source
Mitochondrial biogenesis: An update
Journal of Cellular and Molecular Medicine, 2020 In response to the energy demand triggered by developmental signals and environmental stressors, the cells launch the mitochondrial biogenesis process. This is a self‐renewal route, by which new mitochondria are generated from the ones already existing ...
Lucia-Doina Popov
semanticscholar +1 more source
Distinct fission signatures predict mitochondrial degradation or biogenesis
Nature, 2021 Mitochondrial fission is a highly regulated process that, when disrupted, can alter metabolism, proliferation and apoptosis1–3. Dysregulation has been linked to neurodegeneration3,4, cardiovascular disease3 and cancer5.
Tatjana Kleele +10 more
semanticscholar +1 more source
Autophagy Reports, 2022 Differentiating stem cells must adapt their mitochondrial metabolism to fit the needs of the mature differentiated cell. In a recent study, we observed that during differentiation to an endothelial phenotype, pluripotent stem cell mitochondria are ...
Priyanka Gajwani, Jalees Rehman
doaj +1 more source
Frontiers in Pharmacology, 2022 Neuropathic pain is a devastating disease that affects millions of people worldwide. Serotonin (5-hydroxytryptamine, 5-HT) is involved in pain modulation.
Long-Qing Zhang +8 more
doaj +1 more source
Hsp70 in mitochondrial biogenesis [PDF]
, 1994 The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff +53 more
core +1 more source
Biogenesis of mitochondrial porin [PDF]
, 1990 We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann +74 more
core +1 more source