Results 11 to 20 of about 123,664 (300)

Biogenesis of mitochondrial proteins [PDF]

open access: yesCurrent Opinion in Cell Biology, 1996
Numerous components have been identified that participate at various stages in the biogenesis of mitochondria. For many of these components, their specific functions have recently been defined through detailed investigations of the molecular mechanisms underlying protein targeting, translocation across the mitochondrial outer and inner membranes ...
R, Lill, F E, Nargang, W, Neupert
core   +8 more sources

Regulation of Mitochondrial Biogenesis in Diabetic Retinopathy [PDF]

open access: yesCells
Mitochondrial dysfunction plays a major role in diabetic retinopathy development and in its resistance to halt after the reversal of hyperglycemia (metabolic memory).
Jay Kumar, Renu A. Kowluru
doaj   +2 more sources

Mitochondrial biogenesis and turnover [PDF]

open access: yesCell Calcium, 2008
Mitochondrial biogenesis is a complex process involving the coordinated expression of mitochondrial and nuclear genes, the import of the products of the latter into the organelle and turnover. The mechanisms associated with these events have been intensively studied in the last 20 years and our understanding of their details is much improved ...
Francisca, Diaz, Carlos T, Moraes
openaire   +3 more sources

Regulation of mitochondrial biogenesis [PDF]

open access: yesEssays in Biochemistry, 2010
Although it is well established that physical activity increases mitochondrial content in muscle, the molecular mechanisms underlying this process have only recently been elucidated. Mitochondrial dysfunction is an important component of different diseases associated with aging, such as Type 2 diabetes and Alzheimer’s disease.
François R, Jornayvaz   +1 more
openaire   +3 more sources

Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes

open access: yesMarine Drugs, 2014
Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Jubert Marquez   +2 more
exaly   +3 more sources

Mitochondrial Biogenesis and Mitochondrial Reactive Oxygen Species (ROS): A Complex Relationship Regulated by the cAMP/PKA Signaling Pathway

open access: yesCells, 2019
Mitochondrial biogenesis is a complex process. It requires the contribution of both the nuclear and the mitochondrial genomes and therefore cross talk between the nucleus and mitochondria.
Anne Devin, Devin Anne
exaly   +3 more sources

DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation [PDF]

open access: yesCell Communication and Signaling
Background Remodeling of the mitochondrial network is implicated in myogenesis. Remodeling processes including mitochondrial fission, mitophagy, and biogenesis are important as they finetune the mitochondrial network to meet the increased energetic ...
Fasih A. Rahman   +5 more
doaj   +2 more sources

Histone Lactylation Couples FSH-Driven Lactate Metabolism to Mitochondrial Biogenesis by Enhancing HDAC4-Mediated Deacetylation of PGC-1α in Granulosa Cells [PDF]

open access: yesResearch
Follicle-stimulating hormone (FSH) coordinates ovarian follicle development by aligning mitochondrial biogenesis with increased metabolic demand. Although FSH is known to stimulate glycolysis in granulosa cells (GCs), the mechanism by which glycolytic ...
Gang Wu   +13 more
doaj   +2 more sources

Mitochondrial biogenesis and healthy aging [PDF]

open access: yesExperimental Gerontology, 2008
Aging is associated with an overall loss of function at the level of the whole organism that has origins in cellular deterioration. Most cellular components, including mitochondria, require continuous recycling and regeneration throughout the lifespan.
López-Lluch, Guillermo   +3 more
openaire   +4 more sources

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