Results 31 to 40 of about 535,437 (290)

5-HT1F Receptor Agonist Ameliorates Mechanical Allodynia in Neuropathic Pain via Induction of Mitochondrial Biogenesis and Suppression of Neuroinflammation

Frontiers in Pharmacology, 2022
Neuropathic pain is a devastating disease that affects millions of people worldwide. Serotonin (5-hydroxytryptamine, 5-HT) is involved in pain modulation.
Long-Qing Zhang, Ya-Qun Zhou, Jia-Yan Li, Jia Sun, Shuang Zhang, Jia-Yi Wu, Shao-Jie Gao, Xue-Bi Tian, Wei Mei   +8 more
doaj   +1 more source

Alternative oxidase dependent respiration leads to an increased mitochondrial content in two long-lived mutants of the aging model Podospora anserina [PDF]

, 2011
The retrograde response constitutes an important signalling pathway from mitochondria to the nucleus which induces several genes to allow compensation of mitochondrial impairments.
Koen Houthoofd, Jacques R. Vanfleteren, Werner, Alexandra, Christian Q. Scheckhuber, De Vreese, Annemie, Scheckhuber Christian Q., Andrea C. Weil, Heinz D. Osiewacz, Jacques R Vanfleteren, Osiewacz, Heinz D., Scheckhuber, Christian Quintus, Christian Q Scheckhuber, De Vreese Annemie, Houthoofd Koen, Vanfleteren Jacques R., Vanfleteren, Jacques R., Weil Andrea C., Andrea C Weil, Werner Alexandra, Heinz D Osiewacz, Houthoofd, Koen, Osiewacz Heinz D., Alexandra Werner, Annemie De Vreese, Weil, Andrea C.   +24 more
core   +1 more source

Potensi Konsumsi Kunyit Dalam Rangka Meningkatkan Performa Olahraga Melalui Peningkatan Mitokondria Biogenesis Otot Skelet

Jurnal Pendidikan Jasmani dan Olahraga, 2018
One of physical adaptation at cell level is known as mitochondrial biogenesis. Sport endurance could increase the metabolic characteristic in skeletal muscle, including mitochondrial biogenesis and glucose transporter 4 (GLUT4) improvement.
Hamidie Ronald Daniel Ray, Kazumi Masuda
doaj   +1 more source

Biogenesis of Mitochondrial Metabolite Carriers [PDF]

Biomolecules, 2020
Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers have to be imported into mitochondria from the cytosol.
Patrick Horten, Lilia Colina-Tenorio, Heike Rampelt   +2 more
openaire   +4 more sources

Biosynthetic pathway of mitochondrial ATPase subunit 9 in Neurospora crassa [PDF]

, 1983
Subunit 9 of mitochondrial ATPase (Su9) is synthesized in reticulocyte lysates programmed with Neurospora poly A-RNA, and in a Neurospora cell free system as a precursor with a higher apparent molecular weight than the mature protein (Mr 16,400 vs.
Zimmermann, Richard, Neupert, Walter, Hennig, Bernd, Schmidt, Bernd   +3 more
core   +2 more sources

ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major [PDF]

, 2012
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system, which is required for ATG8-dependent autophagosome ...
Williams, Roderick A M, Mottram, Jeremy C, Roderick A M Williams, Benjamin Cull, Mottram Jeremy C., Coombs, Graham H, Williams Roderick A. M., Cull Benjamin, Terry K Smith, Jeremy C. Mottram (112563), Graham H. Coombs (164011), Smith Terry K., Terry K. Smith (112550), Mottram, Jeremy C., Benjamin Cull (164010), Coombs Graham H., Coombs, Graham H., Smith, Terry K., Jeremy C Mottram, Smith, Terry K, Cull, Benjamin, Williams, Roderick A. M., Roderick A. M. Williams (164005), Graham H Coombs   +23 more
core   +1 more source

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

mBio, 2016
Infection with human cytomegalovirus (HCMV) profoundly affects cellular metabolism. Like in tumor cells, HCMV infection increases glycolysis, and glucose carbon is shifted from the mitochondrial tricarboxylic acid cycle to the biosynthesis of fatty acids.
S. Karniely, M. P. Weekes, R. Antrobus, J. Rorbach, L. van Haute, Y. Umrania, D. L. Smith, R. J. Stanton, M. Minczuk, P. J. Lehner, J. H. Sinclair   +10 more
doaj   +1 more source

Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes

Ecotoxicology and Environmental Safety, 2021
Improper treatment of a large amount of industrial waste makes hexavalent chromium [Cr(VI)] seriously pollute the atmosphere, soil and water, and enter the food chain, seriously affecting the health of workers and local residents.
Ningjuan Liang, Siwen Li, Yuehui Liang, Yu Ma, Sixuan Tang, Shuzi Ye, Fang Xiao   +6 more
doaj   +1 more source

Modulating Ubiquinone Biosynthesis Rescues Mitochondrial Dysfunction by Genetic Interaction in a Phosphatidylethanolamine (PE)-Deficient Disease Model

Antioxidants
Mitochondrial dysfunctions are often associated with cellular aging as well as metabolic disorders. Therapeutic strategies for rewiring mitochondrial stress signaling in a disease context could be beneficial.
Lavanya Vadupu, Vijay Aditya Mavuduru, Writoban Basu Ball   +2 more
doaj   +1 more source

Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome

Nature Communications, 2023
Mitochondria contain their own genetic information and a dedicated translation system to express it. The mitochondrial ribosome is assembled from mitochondrial-encoded RNA and nuclear-encoded ribosomal proteins.
Thu Giang Nguyen, Christina Ritter, Eva Kummer   +2 more
doaj   +1 more source