Results 31 to 40 of about 114,000 (255)

Functional characterisation of PREL-1 and PREL-3 proteins as putative intramitochondrial phospholipid transporters governing homeostasis and organismal health in Caenorhabditis elegans

open access: yesFrontiers in Molecular Biosciences
IntroductionMitochondrial phospholipids are crucial for maintaining structure and function; however, their roles and transport pathways are not fully understood in a multicellular model organism.
Vijay Aditya Mavuduru   +4 more
doaj   +1 more source

Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle

open access: yesBMC Pulmonary Medicine, 2020
Background Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature.
Pieter A. Leermakers   +4 more
doaj   +1 more source

Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

open access: yesAdipocyte, 2022
Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes (T2DM). Decreased mitochondrial abundance and function were found in white adipose tissue (WAT) of T2DM patients.
Jialin Sun   +8 more
doaj   +1 more source

A perspective on the determination of mitochondrial biogenesis [PDF]

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 2012
The measurement of mitochondrial biogenesis is important in the determination of aging and disease processes and the assessment of countermeasurements to them. We argue that the frequently used assessments of cell signaling, mitochondrial protein mRNA, mitochondrial protein expression or enzyme activity, and mitochondrial density are not measurements ...
Benjamin F, Miller, Karyn L, Hamilton
openaire   +2 more sources

Upregulation of Mitochondrial Content in Cytochrome c Oxidase Deficient Fibroblasts. [PDF]

open access: yesPLoS ONE, 2016
Cytochrome-c-oxidase (COX) deficiency is a frequent cause of mitochondrial disease and is associated with a wide spectrum of clinical phenotypes. We studied mitochondrial function and biogenesis in fibroblasts derived from the Cohen (CDs) rat, an animal ...
Aviram Kogot-Levin   +6 more
doaj   +1 more source

Role of TRPV1 in High Temperature-Induced Mitochondrial Biogenesis in Skeletal Muscle: A Mini Review

open access: yesFrontiers in Cell and Developmental Biology, 2022
Transient receptor potential vanilloid 1 (TRPV1) is a protein that is susceptible to cell environment temperature. High temperatures of 40–45°C can activate the TRPV1 channel.
Yixiao Xu, Yongcai Zhao, Binghong Gao
doaj   +1 more source

Nitric oxide and mitochondrial biogenesis [PDF]

open access: yesJournal of Cell Science, 2006
The characteristic structural organization of mitochondria is the product of synthesis of macromolecules within the mitochondria together with the import of proteins and lipids synthesized outside the organelle. Synthetic and import processes are required for mitochondrial proliferation and might also facilitate the growth of pre-existing mitochondria.
E. Nisoli, M. Carruba
openaire   +4 more sources

Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration

open access: yesScientific Reports, 2021
Abuse of the potent psychostimulant cocaine is widely established to have cardiovascular consequences. The cardiotoxicity of cocaine is mainly associated with oxidative stress and mitochondrial dysfunction.
Shuheng Wen   +4 more
doaj   +1 more source

Energy Metabolism on Mitochondrial Maturation and Its Effects on Cardiomyocyte Cell Fate

open access: yesFrontiers in Cell and Developmental Biology, 2022
Alterations in energy metabolism play a major role in the lineage of cardiomyocytes, such as the dramatic changes that occur in the transition from neonate to newborn.
Kaya L. Persad, Gary D. Lopaschuk
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

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