Results 31 to 40 of about 123,664 (300)

In situ observation of mitochondrial biogenesis as the early event of apoptosis

open access: yesiScience, 2021
Summary: Mitochondrial biogenesis is a cell response to external stimuli which is generally believed to suppress apoptosis. However, during the process of apoptosis, whether mitochondrial biogenesis occurs in the early stage of the apoptotic cells ...
Chang-Sheng Shao   +5 more
doaj   +1 more source

Selenite stimulates mitochondrial biogenesis signaling and enhances mitochondrial functional performance in murine hippocampal neuronal cells. [PDF]

open access: yesPLoS ONE, 2012
Supplementation of selenium has been shown to protect cells against free radical mediated cell damage. The objectives of this study are to examine whether supplementation of selenium stimulates mitochondrial biogenesis signaling pathways and whether ...
Natalia Mendelev   +4 more
doaj   +1 more source

MitoSwap – Mitophagy partnered with compensatory mitochondrial biogenesis during stem cell differentiation

open access: yesAutophagy Reports, 2022
Differentiating stem cells must adapt their mitochondrial metabolism to fit the needs of the mature differentiated cell. In a recent study, we observed that during differentiation to an endothelial phenotype, pluripotent stem cell mitochondria are ...
Priyanka Gajwani, Jalees Rehman
doaj   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

open access: yes, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
Stuart, Rosemary A.   +2 more
core   +1 more source

5-HT1F Receptor Agonist Ameliorates Mechanical Allodynia in Neuropathic Pain via Induction of Mitochondrial Biogenesis and Suppression of Neuroinflammation

open access: yesFrontiers in Pharmacology, 2022
Neuropathic pain is a devastating disease that affects millions of people worldwide. Serotonin (5-hydroxytryptamine, 5-HT) is involved in pain modulation.
Long-Qing Zhang   +8 more
doaj   +1 more source

PGC-1α overexpression promotes mitochondrial biogenesis to protect auditory cells against cisplatin-induced cytotoxicity

open access: yesJournal of Bio-X Research, 2019
. Cisplatin (CDDP)-induced ototoxicity is one of the common adverse effects of cisplatin chemotherapy. Thus far, effective approaches for attenuating hearing loss are unavailable in clinical practice.
Weijian Zhang   +8 more
doaj   +1 more source

Protein translocation across mitochondrial membranes [PDF]

open access: yes, 1992
Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Walter Neupert   +3 more
core   +1 more source

The emerging role of Nrf2 in mitochondrial function [PDF]

open access: yes, 2015
The transcription factor NF-E2 p45-related factor 2 (Nrf2, gene name NFE2L2) allows adaptation and survival under conditions of stress by regulating the gene expression of diverse networks of cytoprotective proteins, including antioxidant, anti ...
Dinkova-Kostova, AT   +4 more
core   +1 more source

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7

open access: yesEMBO Molecular Medicine, 2019
Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors that
Karthik Mohanraj   +13 more
doaj   +1 more source

Potensi Konsumsi Kunyit Dalam Rangka Meningkatkan Performa Olahraga Melalui Peningkatan Mitokondria Biogenesis Otot Skelet

open access: yesJurnal Pendidikan Jasmani dan Olahraga, 2018
One of physical adaptation at cell level is known as mitochondrial biogenesis. Sport endurance could increase the metabolic characteristic in skeletal muscle, including mitochondrial biogenesis and glucose transporter 4 (GLUT4) improvement.
Hamidie Ronald Daniel Ray, Kazumi Masuda
doaj   +1 more source

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