Results 41 to 50 of about 712,444 (333)
Journal of Bio-X Research, 2019 . Cisplatin (CDDP)-induced ototoxicity is one of the common adverse effects of cisplatin chemotherapy. Thus far, effective approaches for attenuating hearing loss are unavailable in clinical practice.
Weijian Zhang +8 more
doaj +1 more source
Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]
, 2018 The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo +11 more
core +2 more sources
Biogenesis of mitochondrial ubiquinol [PDF]
, 1982 The precursor proteins to the subunits of ubiquinol:cytochrome c reductase (cytochrome bc1 complex) of Neurospora crassa were synthesized in a reticulocyte lysate.
Neupert, Walter +3 more
core +1 more source
SIRT3 regulates mitochondrial biogenesis in aging-related diseases
Journal of Biomedical Research, 2022 Sirtuin 3 (SIRT3), the main family member of mitochondrial deacetylase, targets the majority of substrates controlling mitochondrial biogenesis via lysine deacetylation and modulates important cellular functions such as energy metabolism, reactive oxygen
Hong-Yan Li, Zhijing Cai
semanticscholar +1 more source
Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7
EMBO Molecular Medicine, 2019 Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors that
Karthik Mohanraj +13 more
doaj +1 more source
Mitochondrial Biogenesis: Pharmacological Approaches [PDF]
, 2014 yesOrganelle biogenesis is concomitant to organelle inheritance during cell division. It is necessary that organelles double their size and divide to give rise to two identical daughter cells. Mitochondrial biogenesis occurs by growth and division of pre-
Valero-Grinan, Teresa M.
core +1 more source
Frontiers in Physiology, 2021 Regular exercise training induces mitochondrial biogenesis in the brain via activation of peroxisome proliferator-activated receptor gamma-coactivator 1α (PGC-1α). However, it remains unclear whether a single bout of exercise would increase mitochondrial
Jonghyuk Park, Jimmy Kim, T. Mikami
semanticscholar +1 more source
Jurnal Pendidikan Jasmani dan Olahraga, 2018 One of physical adaptation at cell level is known as mitochondrial biogenesis. Sport endurance could increase the metabolic characteristic in skeletal muscle, including mitochondrial biogenesis and glucose transporter 4 (GLUT4) improvement.
Hamidie Ronald Daniel Ray, Kazumi Masuda
doaj +1 more source
Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]
, 2016 Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F. +4 more
core +1 more source
Frontiers in Physiology, 2021 Skeletal muscle adaptations to resistance and endurance training include increased ribosome and mitochondrial biogenesis, respectively. Such adaptations are believed to contribute to the notable increases in hypertrophy and aerobic capacity observed with
Paulo H. C. Mesquita +6 more
semanticscholar +1 more source