Results 51 to 60 of about 712,444 (333)

Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes

open access: yesEcotoxicology and Environmental Safety, 2021
Improper treatment of a large amount of industrial waste makes hexavalent chromium [Cr(VI)] seriously pollute the atmosphere, soil and water, and enter the food chain, seriously affecting the health of workers and local residents.
Ningjuan Liang   +6 more
doaj   +1 more source

Tom70-based transcriptional regulation of mitochondrial biogenesis and aging

open access: yesbioRxiv, 2021
Mitochondrial biogenesis has two major steps: the transcriptional activation of nuclear genome-encoded mitochondrial proteins and the import of nascent mitochondrial proteins that are synthesized in the cytosol.
Qingqing Liu   +5 more
semanticscholar   +1 more source

Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome

open access: yesNature Communications, 2023
Mitochondria contain their own genetic information and a dedicated translation system to express it. The mitochondrial ribosome is assembled from mitochondrial-encoded RNA and nuclear-encoded ribosomal proteins.
Thu Giang Nguyen   +2 more
doaj   +1 more source

Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes

open access: yesMarine Drugs, 2014
Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Seung Hun Jeong   +11 more
doaj   +1 more source

Biogenesis of mitochondrial c-type cytochromes [PDF]

open access: yes, 1990
Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core   +2 more sources

Role of TRPV1 in High Temperature-Induced Mitochondrial Biogenesis in Skeletal Muscle: A Mini Review

open access: yesFrontiers in Cell and Developmental Biology, 2022
Transient receptor potential vanilloid 1 (TRPV1) is a protein that is susceptible to cell environment temperature. High temperatures of 40–45°C can activate the TRPV1 channel.
Yixiao Xu, Yongcai Zhao, Binghong Gao
doaj   +1 more source

Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

open access: yesAdipocyte, 2022
Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes (T2DM). Decreased mitochondrial abundance and function were found in white adipose tissue (WAT) of T2DM patients.
Jialin Sun   +8 more
doaj   +1 more source

Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. [PDF]

open access: yes, 2015
Sirtuin (Sirt) 1 and Sirt 3 are nicotinamide adenine dinucleotide ((+))-dependent protein deacetylases that are important to a number of mitochondrial-related functions; thus, identification of sirtuin activators is important. Herein, we hypothesize that
Arguelles, Andrix   +6 more
core   +1 more source

The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases

open access: yesBiomolecules, 2020
Chronic kidney disease (CKD) is one of the fastest growing causes of death worldwide, emphasizing the need to develop novel therapeutic approaches. CKD predisposes to acute kidney injury (AKI) and AKI favors CKD progression.
Miguel Fontecha-Barriuso   +8 more
semanticscholar   +1 more source

Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration

open access: yesScientific Reports, 2021
Abuse of the potent psychostimulant cocaine is widely established to have cardiovascular consequences. The cardiotoxicity of cocaine is mainly associated with oxidative stress and mitochondrial dysfunction.
Shuheng Wen   +4 more
doaj   +1 more source

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