Results 151 to 160 of about 613,759 (317)

Mitochondrial DNA signals of late glacial recolonization of Europe from near Eastern refugia

, 2012
Human populations, along with those of many other species, are thought to have contracted into a number of refuge areas at the height of the last Ice Age.
Reisberg T., Tamm, Erika, Karmin, M., Pereira, L., Al Zahery N., Houshmand M., Tamm, E, Macaulay V, Reisberg, T., Pala M., Gamble C., Villems R, Houshmand M, Macaulay, V., Karmin M., Hatina J, Reisberg, Tuuli, Gamble, Clive, Kashani, Baharak Hooshiar, Accetturo, M., Baird D, Woodward S. R., Woodward SR, Accetturo, M, Reidla, M, Sanati, Mohammad Hossein, Gamble, C, Davies W, Carossa, V., Karmin M, Achilli, A., Kashani, B.H., Reisberg, T, Carelli, Valerio, Macaulay, Vincent, Tamm E, Soares, Pedro, Achilli, A, Torroni, Antonio, Sanati M. H., Soares, P, Woodward, SR, Hooshiar Kashani, Baharak, Carossa, V, Torroni, A, Villems, Richard, Rychkov, Sergei, Rychkov S, Richards, MB, Metspalu E., Gandini, F., Karmin, Monika, Pereira, Joana B., Al Zahery N, Metspalu, E., Richards, M.B., PEREGO, UGO ALESSANDRO, Achilli A., Semino, O, Soares P., Olivieri, A, Soares P, Karmin, M, Angerhofer N, Carelli, V., Torroni A., Hatina J., Pala, M., Pereira L, Davies, W, Villems, R, Carelli V, Pereira, J.B., Perego, U.A., Davies, William, Richards MB, Gandini, F, Torroni, A., Reidla, Maere, Olivieri A., Olivieri, Anna, Hatina, J, Perego, Ugo A., Semino, O., Davies, W., Woodward, Scott R., Baird D., Richards M. B., Hooshiar Kashani B., Macaulay V., Villems R., Al-Zahery, N, Metspalu, E, Rychkov, S., Pereira L., Al-Zahery, N., Baird, Douglas, Reisberg T, Angerhofer, N, Pereira JB, Pereira, L, Gandini, Francesca, Gamble C, Sanati MH, Olivieri, A., Hatina, J., Accetturo, Matteo, Pereira, Luísa, Gamble, C., Houshmand, Massoud, Pala, M, Carossa, Valeria, Woodward, S.R., Reidla M, Hossein Sanati, M, Pala, Maria, Angerhofer N., Semino O., Al-Zahery, Nadia, Metspalu, Ene, Davies W., Macaulay, V, Perego U. A., Houshmand, M., Angerhofer, N., Sanati, M.H., Houshmand, M, Tamm E., Pereira, JB, Baird, D, Metspalu E, Achilli, Alessandro, Angerhofer, Norman, Carelli, V, Semino, Ornella, Villems, R., Pereira J. B., Carossa V., Reidla M., Rychkov S., Hooshiar Kashani, B, Perego, UA, Hatina, Jiři, Richards, Martin B., Baird, D., Soares, P., Gandini F., Accetturo M., Rychkov, S   +148 more
core   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Mitochondrial DNA signature for range-wide populations of Bicyclus anynana suggests a rapid expansion from recent refugia

, 2011
This study investigates the genetic diversity, population structure and demographic history of the afrotropical butterfly Bicyclus anynana using mitochondrial DNA (mtDNA).
Eijk, M., van, Jong, M.A., de, Wahlberg, N., Zwaan, B.J., Brakefield, P.M.   +4 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

The complete mitochondrial genome sequence of Acentrogobius caninus (Gobiiformes: Gobiidae)

, 2018
At present, only several species of genus Acentrogobius were described and information of mitochondrial DNA were also just focused on two species.
Shi, Wei, Yu, Hui, Yang, Min
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source