Results 131 to 140 of about 2,304,385 (312)

The Multifaceted Origin of Taurine Cattle Reflected by the Mitochondrial Genome [PDF]

, 2009
A Neolithic domestication of taurine cattle in the Fertile Crescent from local aurochsen (Bos primigenius) is generally accepted, but a genetic contribution from European aurochsen has been proposed.
Malusà, Arianna, Perego, Ugo A., Baharak Hooshiar Kashani, Baharak Hooshiar, Bandelt, Hans-Jürgen, Ferretti, Luca, Pala, Maria, Paolo Ajmone-Marsan, Silvia Bonfiglio, BANDELT HJ, Ugo A Perego, PEREGO, UGO ALESSANDRO, Hans-Jürgen Bandelt, Antonio Torroni, Ornella Semino, Ajmone-Marsan, Paolo, Ro Achilli, Achilli, Alessandro, Liotta, Luigi, Semino, Ornella, Anna Olivieri, LIOTTA L, Ajmone Marsan, Paolo, AJMONE MARSAN P, Luca Ferretti, Luigi Liotta, Torroni, Antonio, Maria Pala, Ugo A. Perego, Alessandro Achilli, Olivieri, Anna, Bonfiglio, Silvia, Arianna Malusà, Hooshiar Kashani, Baharak, MALUSA', ARIANNA, Bonfiglio S., Achilli Alessandro, Hooshiar Kashani B, Ajmone-Marsan Paolo, Pala M., Torroni Antonio, Kashani B. H., Bonfiglio S, Bandelt H. J., Liotta Luigi, Kashani Baharak Hooshiar, Ferretti L., Olivieri Anna, Malusà Arianna, Ajmone Marsan P., Perego UA, Semino O., Malusà A, Achilli A., Lotta L, Malusà A., Perego U. A., Bonfiglio Silvia, Bandelt Hans-Jürgen, Pala Maria, Ferretti Luca, Torroni A., Olivieri A, Semino Ornella, Semino O, Perego Ugo A., Olivieri A., Ferretti L, Pala M   +68 more
core   +2 more sources

Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India

Tumor Biology, 2017
Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar, Shilpee Srivastava, Seram Anil Singh, Anup Kumar Das, Ganesh Chandra Das, Bishal Dhar, Sankar Kumar Ghosh, Rosy Mondal   +7 more
doaj   +1 more source

Mitochondrial DNA-related Disorders

Bioscience Reports, 2007
Mitochondrial diseases are a group of disorders due to a mitochondrial respiratory chain deficiency. They may depend on mitochondrial genome (mtDNA-related disorders) as well as on a nuclear genome defect (nDNA-related disorders). mtDNA-related disorders encompass an increasing number of clinical pictures associated with more than 250 different ...
MANCUSO, MICHELANGELO, FILOSTO M, CHOUB A, TENTORIO M, BROGLIO L, PADOVANI A, SICILIANO, GABRIELE   +6 more
openaire   +4 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Mitochondrial DNA and Genetic Disease [PDF]

Developmental Medicine & Child Neurology, 1988
AbstractSince the human mitochondrial genome was characterised and sequenced in 1981(1), it has been viewed as the likely site of genetic diseases showing a maternal inheritance pattern and associated with defects of the respiratory chain, such as the mitochondrial myopathies (MMs)†(2).
openaire   +4 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Complete mitochondrial DNA genome of Triplophysa venusta (Cypriniformes: Cobitida)

, 2016
The complete mitochondrial DNA sequence of Triplophysa venusta was determined using a PCR-based method in our present study. The genome is totally 16 574 bp in length and contains 13 protein-coding genes, 2 ribosomal RNA, 22 transfer RNA genes, and 1 non-
Liang, Yin-Quan, Li, Ming, Zhang, Yu, Wang, Chong, Shen, Zai-Jun, Jiang, Zhi-Wu   +5 more
core   +1 more source

Mitochondrial DNA signature for range-wide populations of Bicyclus anynana suggests a rapid expansion from recent refugia [PDF]

, 2011
This study investigates the genetic diversity, population structure and demographic history of the afrotropical butterfly Bicyclus anynana using mitochondrial DNA (mtDNA).
Eijk, M., van, Jong, M.A., de, Wahlberg, N., Zwaan, B.J., Brakefield, P.M.   +4 more
core   +1 more source