Results 111 to 120 of about 2,304,385 (312)

Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver [PDF]

, 2005
The largest single underlying cause of hepatocellular carcinoma (HCC) worldwide is hepatitis B virus (HBV) infection. Hepatitis B virus increases cellular oxidative stress and the development of HCC occurs after a long latency period.
J A Ross, Wheelhouse, Nicholas M, D J Harrison, Wigmore, S J, Lai, P B S, P B S Lai, Wheelhouse, N M, Ross, J A, Harrison, D J, N M Wheelhouse, S J Wigmore   +10 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Wolbachia and DNA barcoding insects: patterns, potential and problems [PDF]

, 2012
Wolbachia is a genus of bacterial endosymbionts that impacts the breeding systems of their hosts. Wolbachia can confuse the patterns of mitochondrial variation, including DNA barcodes, because it influences the pathways through which mitochondria are ...
Janzen, D H, Mark R. Shaw (167095), Packer , L, Julie K. Stahlhut (167104), Claudia Bertrand (167052), Dirk Steinke, Xin Zhou, Crosby, K, Yanwei Li (167076), Quicke Donald, Quicke, D, Eveleigh Eldon S., Monty Wood, Steinke Dirk, Stahlhut, J K, Katharine Hind, Fernandez-Triana, J, Shaw, Mark R, Winnie Hallwachs, Hind Katharine, Ratnasingham, S, Da-Wei Huang, Yanwei, L, Katharine Hind (167065), Julie K Stahlhut, Bertrand, C, Eldon S. Eveleigh (167054), Hind, K, Daniel H Janzen, Jason Gibbs (167056), Brian L Fisher, Fisher, B L, Cory Sheffield, Mehrdad Hajibabaei, James Whitfield (167108), Monty Wood (167110), Miller Scott E., Josephine Rodriguez, Brian L. Fisher (47870), Sujeevan Ratnasingham (167085), Kate Crosby, Donald Quicke, Wood Monty, Janda Milan, Jan Hrcek (167068), Huang Da-Wei, Ratnasingham Sujeevan, Gibbs, J, Hallwachs Winnie, Huang, D W, Rodriguez, J J, Kate Crosby (167053), Laurence Packer, Scott E. Miller (167079), Eldon S Eveleigh, Smith M. Alex, James Whitfield, Zhou, X, Scott E Miller, Zhou Xin, Rodolphe Rougerie (134289), Yanwei Li, Janda, M, Crosby Kate, Hrcek, J, Cory Sheffield (167100), Whitfield, J B, Jason Gibbs, Wood, M, M Alex Smith, Rodolphe Rougerie, Smith, M A, Sheffield Cory, Rougerie Rodolphe, Hallwachs, W, Donald Quicke (167083), Fisher Brian L., Sheffield, C, Jan Hrcek, Rodriguez Josephine, Mehrdad Hajibabaei (76205), Packer Laurence, Stahlhut Julie K., Whitfield James, M. Alex Smith (47871), Winnie Hallwachs (167061), Wood , M, Milan Janda, Bertrand Claudia, Gibbs Jason, Da-Wei Huang (102802), Miller, S E, Dirk Steinke (15543), Laurence Packer (167080), Mark R Shaw, Li Yanwei, Packer, L, Hajibabaei Mehrdad, Rougerie, R, Claudia Bertrand, Hrcek Jan, Sujeevan Ratnasingham, Daniel H. Janzen (167074), Fernandez-Triana Jose, Steinke, D, Jose Fernandez-Triana (167055), Milan Janda (167072), Josephine Rodriguez (167090), Hajibabaei, M, Xin Zhou (54275), Jose Fernandez-Triana, Janzen Daniel H., Shaw Mark R., Eveleigh, E S, Janda , M   +114 more
core   +1 more source

RETRACTED: MtDNA polymorphism analyses in the Chinese Mongolian group: Efficiency evaluation and further matrilineal genetic structure exploration

Molecular Genetics & Genomic Medicine, 2019
Background Profiling of mitochondrial DNA is surely to provide valuable investigative clues for forensic cases involving highly degraded specimens or complex maternal lineage kinship determination.
Qiong Lan, Tong Xie, Xiaoye Jin, Yating Fang, Shuyan Mei, Guang Yang, Bofeng Zhu   +6 more
doaj   +1 more source

Mitochondrial DNA mitochondrial dysfunction and cardiac manifestations

Frontiers in Bioscience, 2016
Mitochondria, the powerhouses of cells, have their own DNA (mtDNA). They regulate the transport of metabolites and ions, which determine cell physiology, survival, and death. Mitochondrial dysfunction, including impaired oxidative phosphorylation, preferentially affects heart function via imbalance of energy supply and demand.
Sung Ryul, Lee, Nari, Kim, Yeun Hee, Noh, Zhelong, Xu, Kyung Soo, Ko, Byoung Doo, Rhee, Jin, Han   +6 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Mitochondrial DNA signals of late glacial recolonization of Europe from near Eastern refugia [PDF]

, 2012
Human populations, along with those of many other species, are thought to have contracted into a number of refuge areas at the height of the last Ice Age.
Reisberg T., Tamm, Erika, Karmin, M., Pereira, L., Al Zahery N., Houshmand M., Tamm, E, Macaulay V, Reisberg, T., Pala M., Gamble C., Villems R, Houshmand M, Macaulay, V., Karmin M., Hatina J, Reisberg, Tuuli, Gamble, Clive, Kashani, Baharak Hooshiar, Accetturo, M., Baird D, Woodward S. R., Woodward SR, Accetturo, M, Reidla, M, Sanati, Mohammad Hossein, Gamble, C, Davies W, Carossa, V., Karmin M, Achilli, A., Kashani, B.H., Reisberg, T, Carelli, Valerio, Macaulay, Vincent, Tamm E, Soares, Pedro, Achilli, A, Torroni, Antonio, Sanati M. H., Soares, P, Woodward, SR, Hooshiar Kashani, Baharak, Carossa, V, Torroni, A, Villems, Richard, Rychkov, Sergei, Rychkov S, Richards, MB, Metspalu E., Gandini, F., Karmin, Monika, Pereira, Joana B., Al Zahery N, Metspalu, E., Richards, M.B., PEREGO, UGO ALESSANDRO, Achilli A., Semino, O, Soares P., Olivieri, A, Soares P, Karmin, M, Angerhofer N, Carelli, V., Torroni A., Hatina J., Pala, M., Pereira L, Davies, W, Villems, R, Carelli V, Pereira, J.B., Perego, U.A., Davies, William, Richards MB, Gandini, F, Torroni, A., Reidla, Maere, Olivieri A., Olivieri, Anna, Hatina, J, Perego, Ugo A., Semino, O., Davies, W., Woodward, Scott R., Baird D., Richards M. B., Hooshiar Kashani B., Macaulay V., Villems R., Al-Zahery, N, Metspalu, E, Rychkov, S., Pereira L., Al-Zahery, N., Baird, Douglas, Reisberg T, Angerhofer, N, Pereira JB, Pereira, L, Gandini, Francesca, Gamble C, Sanati MH, Olivieri, A., Hatina, J., Accetturo, Matteo, Pereira, Luísa, Gamble, C., Houshmand, Massoud, Pala, M, Carossa, Valeria, Woodward, S.R., Reidla M, Hossein Sanati, M, Pala, Maria, Angerhofer N., Semino O., Al-Zahery, Nadia, Metspalu, Ene, Davies W., Macaulay, V, Perego U. A., Houshmand, M., Angerhofer, N., Sanati, M.H., Houshmand, M, Tamm E., Pereira, JB, Baird, D, Metspalu E, Achilli, Alessandro, Angerhofer, Norman, Carelli, V, Semino, Ornella, Villems, R., Pereira J. B., Carossa V., Reidla M., Rychkov S., Hooshiar Kashani, B, Perego, UA, Hatina, Jiři, Richards, Martin B., Baird, D., Soares, P., Gandini F., Accetturo M., Rychkov, S   +148 more
core   +1 more source

Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction

Redox Biology, 2015
High levels of oxygen (hyperoxia) are often used to treat individuals with respiratory distress, yet prolonged hyperoxia causes mitochondrial dysfunction and excessive reactive oxygen species (ROS) that can damage molecules such as DNA.
Emily A. Resseguie, Rhonda J. Staversky, Paul S. Brookes, Michael A. O’Reilly   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The role of mitochondrial DNA in tumorigenesis [PDF]

Mitochondria are cytoplasmic organelles that are found in almost all mammalian cells. Mitochondria contain their own genome, mitochondrial DNA (mtDNA) that encodes 13 subunits of the electron transfer chain, which is the primary generator of cellular ...
Dickinson, Adam
core