Results 121 to 130 of about 613,759 (317)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Complete mitochondrial DNA genome of Triplophysa venusta (Cypriniformes: Cobitida)

, 2016
The complete mitochondrial DNA sequence of Triplophysa venusta was determined using a PCR-based method in our present study. The genome is totally 16 574 bp in length and contains 13 protein-coding genes, 2 ribosomal RNA, 22 transfer RNA genes, and 1 non-
Liang, Yin-Quan, Li, Ming, Zhang, Yu, Wang, Chong, Shen, Zai-Jun, Jiang, Zhi-Wu   +5 more
core   +1 more source

The Multifaceted Origin of Taurine Cattle Reflected by the Mitochondrial Genome [PDF]

, 2009
A Neolithic domestication of taurine cattle in the Fertile Crescent from local aurochsen (Bos primigenius) is generally accepted, but a genetic contribution from European aurochsen has been proposed.
Malusà, Arianna, Perego, Ugo A., Baharak Hooshiar Kashani, Baharak Hooshiar, Bandelt, Hans-Jürgen, Ferretti, Luca, Pala, Maria, Paolo Ajmone-Marsan, Silvia Bonfiglio, BANDELT HJ, Ugo A Perego, PEREGO, UGO ALESSANDRO, Hans-Jürgen Bandelt, Antonio Torroni, Ornella Semino, Ajmone-Marsan, Paolo, Ro Achilli, Achilli, Alessandro, Liotta, Luigi, Semino, Ornella, Anna Olivieri, LIOTTA L, Ajmone Marsan, Paolo, AJMONE MARSAN P, Luca Ferretti, Luigi Liotta, Torroni, Antonio, Maria Pala, Ugo A. Perego, Alessandro Achilli, Olivieri, Anna, Bonfiglio, Silvia, Arianna Malusà, Hooshiar Kashani, Baharak, MALUSA', ARIANNA   +34 more
core   +1 more source

Mitochondrial DNA-related Disorders

Bioscience Reports, 2007
Mitochondrial diseases are a group of disorders due to a mitochondrial respiratory chain deficiency. They may depend on mitochondrial genome (mtDNA-related disorders) as well as on a nuclear genome defect (nDNA-related disorders). mtDNA-related disorders encompass an increasing number of clinical pictures associated with more than 250 different ...
MANCUSO, MICHELANGELO, FILOSTO M, CHOUB A, TENTORIO M, BROGLIO L, PADOVANI A, SICILIANO, GABRIELE   +6 more
openaire   +4 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A study of mitochondrial biogenesis in the rodent nervous system

, 2015
This thesis investigates the process of mitochondrial biogenesis in the rodent CNS in the context of neuroinflammatory and neurodegenerative disease. There is mounting evidence of mitochondrial damage in neuroinflammation but very little is known about ...
Desai, R
core  

Phylogenetic study of Ameiurus melas based on complete mitochondrial DNA sequence

, 2016
In our research, 16 sets of primers were used to amplify contiguous, overlapping segments of the complete mitochondrial DNA (mtDNA) of Ameiurus melas. The total length of the mitochondrial genome is 16 512 bp and deposited in the GenBank with accession ...
Yu, Juhua, Fang, Yanhong, Zhou, Yi, Wang, Wenjun, Yang, Zhong, Yan, Jinpeng, Yu, Fan   +6 more
core   +1 more source

Mitochondrial DNA and Disease

Annals of Medicine, 1997
Mitochondrial diseases are a group of disorders characterized by morphological or functional defects of the mitochondria, the organelles producing most of our cellular energy. As the only extranuclear site carrying genetic information, the mitochondria add an important chapter into the inheritance patterns of genetic diseases. Mitochondrial DNA (mtDNA)
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Deceleration of fusion–fission cycles improves mitochondrial quality control during aging

, 2012
Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer.
Michael Meyer-Hermann, Michael Meyer-Hermann (124166), Andreas S. Reichert (124162), Reichert Andreas S., Heinz D. Osiewacz (120841), Figge, Marc Thilo, Reichert, Andreas S, Marc Thilo Figge, Heinz D Osiewacz, Reichert, Andreas, Meyer-Hermann Michael, Meyer-Hermann, Michael (Prof. Dr.), Osiewacz Heinz D., Meyer-Hermann, Michael, Osiewacz, Heinz D., Andreas S Reichert, Figge Marc Thilo, Marc Thilo Figge (155511), Osiewacz, Heinz D   +18 more
core   +1 more source