Results 141 to 150 of about 41,598 (256)

Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease. [PDF]

CNS Neurosci Ther
Qiao C, Hu XQ, Xu SH, Yao MF, Liu JP, Cao L.   +5 more
europepmc   +1 more source

Exercise training to preserve vitality capacity in ageing

Experimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford   +12 more
wiley   +1 more source

VPS13B recruits lipid vesicles to promote mitochondrial fission and quality control. [PDF]

Nat Commun
Lee SK, Ham HJ, Park S, Lee HE, Mun JY, Jang DJ, Lee JA.   +6 more
europepmc   +1 more source

Inhibition of Pathological Mitochondrial Fission in Retinal Pigment Epithelium Mitigates Choroidal Neovascularization. [PDF]

Invest Ophthalmol Vis Sci
Yasuda H, Nakamura S, Shirakawa A, Kuse Y, Shimazawa M.   +4 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis. [PDF]

Oncogenesis
Cai H, He J.
europepmc   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source

Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex. [PDF]

J Cell Biol
Rodriguez Salazar MP, Kolanukuduru S, Ramirez V, Lyu B, Manigault G, Sejourne G, Sesaki H, Yu G, Eroglu C.   +8 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Sirtuin 4 Knockout Aggravates Sepsis-Induced Acute Liver Injury by Enhancing Mitochondrial Fission and Mitophagy in Hepatocytes. [PDF]

Mediators Inflamm
Li N, Ma D, Luo S, He A, Chang S.
europepmc   +1 more source