A rule-based simulation model illuminates the role of asymmetric mitochondrial fission on beta-cell health. [PDF]
Henning P +3 more
europepmc +1 more source
Understanding exosomes in diabetic wound healing
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
TRMT10C promotes mitochondrial fission through transferrin receptor m1A methylation modification and aggravates the progression of atrial fibrillation. [PDF]
Li N, Zhang H.
europepmc +1 more source
HIF1-α induces mitochondrial fission in trophoblastic cells during early pregnancy and in preeclampsia. [PDF]
Poinsignon L +10 more
europepmc +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
ALDOB K87 lactylation drives mitochondrial fission and metabolic reprogramming in pulmonary hypertension. [PDF]
Yi L +8 more
europepmc +1 more source
Mitochondrial fission requires DRP1 but not dynamins
Tiago Branco Fonseca +3 more
openaire +3 more sources
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova +6 more
wiley +1 more source
Resveratrol alleviates neuropathic pain associated with restoration of mitochondrial fission-fusion balance in CCI mice. [PDF]
Xie L +5 more
europepmc +1 more source
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source

