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Mitochondrial calcium shapes B cell signaling and mitochondrial function [PDF]
Frontiers in ImmunologyIntroductionCalcium (Ca2+) signaling plays a pivotal role in determining B cell fate, shaping processes such as activation, differentiation, anergy or apoptosis.
Hakan Taskiran +15 more
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CFTR activity and mitochondrial function
Redox Biology, 2013 Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
Angel Gabriel Valdivieso +1 more
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Evaluating the mitochondrial function [PDF]
Diabetology & Metabolic Syndrome, 2012 We have read the article by Xia et.al. entitled as "L-carnitine ameliorated fatty liver in high-calorie diet/STZ induced type 2 diabetic mice by improving mitochondrial function" with great interest. In this article, the authors concluded that L-carnitine might be an effective liver cell protector for delaying the progression of type 2 diabetes ...
Akgul Emin +2 more
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Mitochondrial Functioning ≠ General Intelligence [PDF]
Journal of Intelligence, 2020 Geary puts forward an appealing argument for the consideration of mitochondrial functioning as a candidate for a formative g Geary (2019); it is also an ambitious argument [...]
Alexander O. Savi +3 more
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European Psychiatry, 2023 Introduction Current evidence has hypothesized the involvement of mitochondrial dysfunction during the acute episodes of BD compared to symptomatic remission.
A. Giménez-Palomo +12 more
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Antioxidants, 2022 Intrauterine growth restriction (IUGR) affects 5–10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al.
Glòria Garrabou +11 more
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The Impact of Mitochondrial Deficiencies in Neuromuscular Diseases
Antioxidants, 2020 Neuromuscular diseases (NMDs) are a heterogeneous group of acquired or inherited rare disorders caused by injury or dysfunction of the anterior horn cells of the spinal cord (lower motor neurons), peripheral nerves, neuromuscular junctions, or skeletal ...
Judith Cantó-Santos +2 more
doaj +1 more source
Relevance of sex-differenced analyses in bioenergetics and nutritional studies
Frontiers in Nutrition, 2022 Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males.
Glòria Garrabou +7 more
doaj +1 more source
Mitochondrial function requires NGLY1 [PDF]
Mitochondrion, 2018 Mitochondrial respiratory chain (RC) diseases and congenital disorders of glycosylation (CDG) share extensive clinical overlap but are considered to have distinct cellular pathophysiology. Here, we demonstrate that an essential physiologic connection exists between cellular N-linked deglycosylation capacity and mitochondrial function.
Jianping, Kong +8 more
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Unravelling inclusion body myositis using a patient‐derived fibroblast model
Journal of Cachexia, Sarcopenia and Muscle, 2023 Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology.
Judith Cantó‐Santos +18 more
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