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Mitochondrial calcium shapes B cell signaling and mitochondrial function [PDF]

open access: yesFrontiers in Immunology
IntroductionCalcium (Ca2+) signaling plays a pivotal role in determining B cell fate, shaping processes such as activation, differentiation, anergy or apoptosis.
Hakan Taskiran   +15 more
doaj   +2 more sources

CFTR activity and mitochondrial function

open access: yesRedox Biology, 2013
Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
Angel Gabriel Valdivieso   +1 more
doaj   +4 more sources

Evaluating the mitochondrial function [PDF]

open access: yesDiabetology & Metabolic Syndrome, 2012
We have read the article by Xia et.al. entitled as "L-carnitine ameliorated fatty liver in high-calorie diet/STZ induced type 2 diabetic mice by improving mitochondrial function" with great interest. In this article, the authors concluded that L-carnitine might be an effective liver cell protector for delaying the progression of type 2 diabetes ...
Akgul Emin   +2 more
doaj   +3 more sources

Mitochondrial Functioning ≠ General Intelligence [PDF]

open access: yesJournal of Intelligence, 2020
Geary puts forward an appealing argument for the consideration of mitochondrial functioning as a candidate for a formative g Geary (2019); it is also an ambitious argument [...]
Alexander O. Savi   +3 more
openaire   +5 more sources

Bioenergetic changes and mitochondrial dysfunction in mania versus euthymia in bipolar disorder type I

open access: yesEuropean Psychiatry, 2023
Introduction Current evidence has hypothesized the involvement of mitochondrial dysfunction during the acute episodes of BD compared to symptomatic remission.
A. Giménez-Palomo   +12 more
doaj   +1 more source

Comment on Yeste et al. Polyphenols and IUGR Pregnancies: Intrauterine Growth Restriction and Hydroxytyrosol Affect the Development and Neurotransmitter Profile of the Hippocampus in a Pig Model. Antioxidants 2021, 10, 1505

open access: yesAntioxidants, 2022
Intrauterine growth restriction (IUGR) affects 5–10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al.
Glòria Garrabou   +11 more
doaj   +1 more source

The Impact of Mitochondrial Deficiencies in Neuromuscular Diseases

open access: yesAntioxidants, 2020
Neuromuscular diseases (NMDs) are a heterogeneous group of acquired or inherited rare disorders caused by injury or dysfunction of the anterior horn cells of the spinal cord (lower motor neurons), peripheral nerves, neuromuscular junctions, or skeletal ...
Judith Cantó-Santos   +2 more
doaj   +1 more source

Relevance of sex-differenced analyses in bioenergetics and nutritional studies

open access: yesFrontiers in Nutrition, 2022
Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males.
Glòria Garrabou   +7 more
doaj   +1 more source

Mitochondrial function requires NGLY1 [PDF]

open access: yesMitochondrion, 2018
Mitochondrial respiratory chain (RC) diseases and congenital disorders of glycosylation (CDG) share extensive clinical overlap but are considered to have distinct cellular pathophysiology. Here, we demonstrate that an essential physiologic connection exists between cellular N-linked deglycosylation capacity and mitochondrial function.
Jianping, Kong   +8 more
openaire   +2 more sources

Unravelling inclusion body myositis using a patient‐derived fibroblast model

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Background Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology.
Judith Cantó‐Santos   +18 more
doaj   +1 more source

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