Results 41 to 50 of about 662,543 (166)
Fertility & Reproduction, 2023 Background and Aims: Aging and obesity are associated with female infertility, with mitochondrial dysfunction proposed as an underlying factor; but our understanding of energy metabolism within the ovary remains limited. Method: This study focused on the
Atsushi Morimoto +8 more
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Mitochondrial Function in Enamel Development
Frontiers in Physiology, 2020 Enamel is the most calcified tissue in vertebrates. Enamel formation and mineralization is a two-step process that is mediated by ameloblast cells during their secretory and maturation stages.
Veronica Costiniti +9 more
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PARP10 (ARTD10) modulates mitochondrial function. [PDF]
PLoS ONE, 2018 Poly(ADP-ribose) polymerase (PARP)10 is a PARP family member that performs mono-ADP-ribosylation of target proteins. Recent studies have linked PARP10 to metabolic processes and metabolic regulators that prompted us to assess whether PARP10 influences ...
Judit Márton +8 more
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GRKs and β-Arrestins: “Gatekeepers” of Mitochondrial Function in the Failing Heart
Frontiers in Pharmacology, 2019 Mitochondrial regulation of energy production, calcium homeostasis, and cell death are critical for cardiac function. Accordingly, the structural and functional abnormalities of these organelles (mitochondrial dysfunction) contribute to developing ...
Daniela Sorriento +4 more
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Evaluation of bioenergetic and mitochondrial function in liver transplantation [PDF]
Clinical and Molecular Hepatology, 2019 Background/Aims We measured changes in mitochondrial function and bioenergetics that occur during ischemia/ reperfusion in fresh liver samples of patients undergoing liver transplantation.
Rui Miguel Martins +5 more
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Understanding structure, function, and mutations in the mitochondrial ATP synthase
Microbial Cell, 2015 The mitochondrial ATP synthase is a multimeric enzyme complex with an overall molecular weight of about 600,000 Da. The ATP synthase is a molecular motor composed of two separable parts: F1 and Fo. The F1 portion contains the catalytic sites for ATP
Ting Xu +2 more
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Mitochondrial peptides modulate mitochondrial function during cellular senescence
Aging, 2018 Cellular senescence is a complex cell fate response that is thought to underlie several age-related pathologies. Despite a loss of proliferative potential, senescent cells are metabolically active and produce energy-consuming effectors, including senescence-associated secretory phenotypes (SASPs).
Kim, Su-Jeong +7 more
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Plant mitochondrial function during anaerobiosis [PDF]
Annals of Botany, 2008 Under hypoxic conditions, plant mitochondria preserve the capacity to oxidize external NADH, NADPH and tricarboxylic acid cycle substrates. Nitrite serves as an alternative electron acceptor at the level of cytochrome oxidase, with possibly complex III and the alternative oxidase also being involved.
Abir U, Igamberdiev, Robert D, Hill
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Estrogenic control of mitochondrial function
Redox Biology, 2020 Sex-based differences in human disease are caused in part by the levels of endogenous sex steroid hormones which regulate mitochondrial metabolism. This review updates a previous review on how estrogens regulate metabolism and mitochondrial function that
Carolyn M. Klinge
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Neurobiology of DiseaseMitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) is the third most common genetically-defined subtype of Neurodegeneration with Brain Iron Accumulation (NBIA), a group of rare, clinically heterogeneous disorders. The MPAN pathomechanism,
Barbara Pakula +13 more
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