Results 11 to 20 of about 498,645 (208)

Mitochondrial membrane potential [PDF]

open access: yesAnalytical Biochemistry, 2018
The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III and IV) is an essential component in the process of energy storage during oxidative phosphorylation. Together with the proton gradient (ΔpH), ΔΨm forms the transmembrane potential of hydrogen ions which is harnessed to make ATP.
Ljubava D, Zorova   +11 more
openaire   +2 more sources

Platelet mitochondrial membrane depolarization reflects disease severity in patients with preeclampsia

open access: yesMolecular Medicine, 2022
Background Thrombocytopenia is a feared complication of preeclampsia (PE) that can additionally complicate the disease course and that carries a poor prognosis.
Bjoern F. Kraemer   +7 more
doaj   +1 more source

Effect of the Mitochondrial Membrane Permeability Transition Pore Promoter Atractyloside on Mitochondrial Damage and Tenderness of Postmortem Beef [PDF]

open access: yesShipin Kexue, 2023
The objective of this study was to investigate the effect of atractyloside, a promoter of the mitochondrial membrane permeability transition pore (MPTP), on mitochondrial membrane permeability, cristae structure, cytochrome c release and tenderness of ...
LIU Chunmei, WEI Qichao, HAN Dong, LI Xia, ZHANG Chunhui, HUANG Feng
doaj   +1 more source

Using flow cytometry for mitochondrial assays

open access: yesMethodsX, 2020
The understanding of how different cell types adapt their metabolism in the face of challenges has been attracting the attention of researchers for many years. Recently, immunologists also started to focus on how the metabolism of immune cells can impact
Lauar de Brito Monteiro   +3 more
doaj   +1 more source

S-15176 Difumarate Salt Can Impair Mitochondrial Function through Inhibition of the Respiratory Complex III and Permeabilization of the Inner Mitochondrial Membrane

open access: yesBiology, 2022
S-15176 difumarate salt, a derivative of the anti-ischemic metabolic drug trimetazidine, has been intensively studied for its impact on cellular metabolism in animal models of ischemia-reperfusion injury of the liver, heart, spinal cord, and other organs.
Natalia V. Belosludtseva   +5 more
doaj   +1 more source

Mitochondrial Membrane Potential Assay [PDF]

open access: yes, 2016
Mitochondrial function, a key indicator of cell health, can be assessed by monitoring changes in mitochondrial membrane potential (MMP). Cationic fluorescent dyes are commonly used tools to assess MMP. We used a water-soluble mitochondrial membrane potential indicator (m-MPI) to detect changes in MMP in HepG2 cells.
Srilatha, Sakamuru   +2 more
openaire   +2 more sources

In vivo quantification of mitochondrial membrane potential

open access: yesNature, 2020
Accepted ...
Nathaniel M. Alpert   +4 more
openaire   +5 more sources

Myocardial Imaging for Mitochondrial Membrane Potential

open access: yesJACC: Cardiovascular Imaging, 2012
Rest and stress myocardial perfusion imaging, described nearly 4 decades ago ([1][1]), is now performed in >9 million people annually in the United States ([2][2]). The procedure provides clinically useful data regardless of whether the tracer is a monovalent cation such as potassium, thallium ...
H William, Strauss, Heiko, Schöder
openaire   +4 more sources

Safranine as a probe of the mitochondrial membrane potential [PDF]

open access: yesFEBS Letters, 1976
One of the most central postulates of the chemiosmotic hypothesis of oxidative phosphorylation is the existence of a large electrochemical proton gradient (protonmotive force) across the mitochondrial membrane [ 1,2] . This gradient, which is composed of a membrane potential and a pH differential, is postulated to be the obligatory link between ...
Åkerman, Karl E.O.   +1 more
openaire   +2 more sources

In-vivo Imaging of Mitochondrial Depolarization of Myocardium With Positron Emission Tomography and a Proton Gradient Uncoupler

open access: yesFrontiers in Physiology, 2020
BackgroundWe recently reported a method using positron emission tomography (PET) and the tracer 18F-labeled tetraphenylphosphonium (18F-TPP+) for mapping the tissue (i.e., cellular plus mitochondrial) membrane potential (ΔΨT) in the myocardium.
Nathaniel M. Alpert   +8 more
doaj   +1 more source

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