Results 41 to 50 of about 498,645 (208)
Marine Drugs, 2017 Meretrix meretrix oligopeptides (MMO) derived from shellfish have important medicinal properties. We previously obtained MMO from alcalase by hydrolysis processes.
Fangfang Huang +4 more
doaj +1 more source
, 2008 Spectroscopic responses of the potentiometric probe 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) were investigated in living cells by means of a time- and space-correlated single photon counting technique.
Ramadass, Radhan, Bereiter-Hahn, Jürgen
core +1 more source
Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation [PDF]
, 2009 CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by ...
Crompton, M. +7 more
core +1 more source
Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis
, 2009 The bacterial PorB porin, an ATP-binding beta-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial
Kepp, Oliver +45 more
core +1 more source
Ubiquitin-proteasome dependent mitochondrial protein quality control [PDF]
, 2014 Dysfunctional mitochondria cause many neurodegenerative disorders and with aging in general, mechanisms of mitochondrial quality control are essential for cellular function.
Benischke, Anne-Sophie
core +1 more source
Mitochondrial membrane potential in cardiac myocytes
Physiological Research, 2002 Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield ...
L, Skárka, B, Ostádal
openaire +2 more sources
Effect of electroacupuncture on mitochondrial function in mice with Parkinson’s disease
针刺研究, 2021 Objective To observe the effect of electroacupuncture(EA) on behavior, tyrosine hydroxylase(TH), mitochondrial complexes Ⅰ—Ⅳ, mitochondrial membrane potential and mitochondrial ultrastructure of Parkinson's disease(PD) mice, so as to explore its ...
HUANG Kai +4 more
doaj
Frontiers in Physiology, 2018 Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single ...
Alexis R. Díaz-Vegas +12 more
doaj +1 more source
Journal of Ovarian Research, 2021 Mitochondrial injury in granulosa cells (GCs) is associated with the pathophysiological mechanism of polycystic ovary syndrome (PCOS). Melatonin reduces the mitochondrial injury by enhancing SIRT1 (NAD-dependent deacetylase sirtuin-1), while the ...
Bo Zheng +5 more
doaj +1 more source
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations
, 2010 Mutations of mitochondrial DNA are associated with a wide spectrum of disorders, primarily affecting the central nervous system and muscle function. The specific consequences of mitochondrial DNA mutations for neuronal pathophysiology are not understood.
Turnbull, Douglass M. +16 more
core +1 more source