Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]
, 2013 Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Howell, Matthew +4 more
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Mitochondrial Membrane Potential Predicts 4-Hour Sperm Motility
Biomedicines, 2020 The evaluation of conventional and biofunctional sperm parameters is of fundamental importance for assessing male reproductive function. Among these, sperm motility is one of the most important parameters. Indeed, asthenozoospermia is a frequent cause of
Angela Alamo +7 more
doaj +1 more source
MOM19, an import receptor for mitochondrial precursor proteins [PDF]
, 1989 We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Söllner, Thomas +4 more
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Neurodegenerative stress related mitochondrial proteostasis [PDF]
, 2015 1.1 Background: Mitochondria are the main site of energy production in most cells. Furthermore, they are involved in a multitude of other essential cellular processes, such as regulating the cellular calcium pool, lipid metabolism and programmed cell ...
Fang, Lei
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Mitochondrial membrane studies using impedance spectroscopy with parallel pH monitoring. [PDF]
PLoS ONE, 2014 A biological microelectromechanical system (BioMEMS) device was designed to study complementary mitochondrial parameters important in mitochondrial dysfunction studies.
Divya Padmaraj +4 more
doaj +1 more source
Evaluating Mitochondrial Membrane Potential in Cells
Bioscience Reports, 2007 Permeant cationic fluorescent probes are widely employed to monitor mitochondrial transmembrane potential and its changes. The application of such potential-dependent probes in conjunction with both fluorescence microscopy and fluorescence spectroscopy allows the monitoring of mitochondrial membrane potential in individual living cells as well as in ...
SOLAINI, GIANCARLO +3 more
openaire +3 more sources
Biosynthetic pathway of mitochondrial ATPase subunit 9 in Neurospora crassa [PDF]
, 1983 Subunit 9 of mitochondrial ATPase (Su9) is synthesized in reticulocyte lysates programmed with Neurospora poly A-RNA, and in a Neurospora cell free system as a precursor with a higher apparent molecular weight than the mature protein (Mr 16,400 vs.
W Neupert +7 more
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Non-Mammalian Vertebrates: Distinct Models to Assess the Role of Ion Gradients in Energy Expenditure
Frontiers in Endocrinology, 2017 Animals store metabolic energy as electrochemical gradients. At least 50% of mammalian energy is expended to maintain electrochemical gradients across the inner mitochondrial membrane (H+), the sarcoplasmic reticulum (Ca++), and the plasma membrane (Na ...
Caroline E. Geisler +2 more
doaj +1 more source
Mitochondrial Membrane Potential in Aging Cells
Neurosignals, 2001 Decreased mitochondrial membrane potential (DeltaPsi(M)) has been found in a variety of aging cell types from several mammalian species. The physiological significance and mechanisms of the decreased DeltaPsi(M) in aging are not well understood. This review considers the generation of DeltaPsi(M) and its role in ATP generation together with factors ...
M M, Sugrue, W G, Tatton
openaire +2 more sources
Successive translocation into and out of the mitochondrial matrix [PDF]
, 1987 We investigated the import and sorting pathways of cytochrome b2 and cytochrome c1, which are functionally located in the intermembrane space of mitochondria.
Ostermann, Joachim +3 more
core +1 more source