Results 31 to 40 of about 704,132 (300)

Platelet mitochondrial membrane potential in Parkinson's disease [PDF]

Annals of Clinical and Translational Neurology, 2014
AbstractObjectiveMitochondrial dysfunction is a hallmark of idiopathic Parkinson's disease (IPD), which has been reported not to be restricted to striatal neurons. However, studies that analyzed mitochondrial function at the level of selected enzymatic activities in peripheral tissues have produced conflicting data. We considered the electron transport
Paul M. A. Antony, Olga Boyd, Christophe Trefois, Wim Ammerlaan, Marek Ostaszewski, Aidos S. Baumuratov, Laura Longhino, Laurent Antunes, Werner Koopman, Rudi Balling, Nico J. Diederich   +10 more
openaire   +3 more sources

Decreased Mitochondrial Membrane Potential Activates the Mitochondrial Unfolded Protein Response

microPublication biology, 2021
Mitochondria are organelles that make ATP by generating a proton gradient across the inner membrane through the action of the electron transport chain (ETC). The gradient is composed of a membrane potential (Δψm) and a concentration gradient (ΔpH). In addition to energy production, mitochondria are recognized as signaling organelles (Chandel 2015), and
Berry, Brandon J., Nieves, Tyrone O., Wojtovich, Andrew P.   +2 more
openaire   +2 more sources

Ca ion transport in smooth muscle mitochondria [PDF]

The Ukrainian Biochemical Journal, 2014
Review focuses on the analysis of literature data and own results concerning properties of mitochondria Са2+ transporting systems and their regu­lation.
L. G. Babich, S. G. Shlykov, S. O. Kosterin   +2 more
doaj   +1 more source

Early steps in mitochondrial protein import [PDF]

, 1990
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A.   +2 more
core   +1 more source

Evaluating Mitochondrial Membrane Potential in Cells

Bioscience Reports, 2007
Permeant cationic fluorescent probes are widely employed to monitor mitochondrial transmembrane potential and its changes. The application of such potential-dependent probes in conjunction with both fluorescence microscopy and fluorescence spectroscopy allows the monitoring of mitochondrial membrane potential in individual living cells as well as in ...
SOLAINI, GIANCARLO, SGARBI, GIANLUCA, LENAZ, GIORGIO, BARACCA, ALESSANDRA   +3 more
openaire   +3 more sources

Mitochondrial membrane studies using impedance spectroscopy with parallel pH monitoring. [PDF]

PLoS ONE, 2014
A biological microelectromechanical system (BioMEMS) device was designed to study complementary mitochondrial parameters important in mitochondrial dysfunction studies.
Divya Padmaraj, Rohit Pande, John H Miller, Jarek Wosik, Wanda Zagozdzon-Wosik   +4 more
doaj   +1 more source

Non-Mammalian Vertebrates: Distinct Models to Assess the Role of Ion Gradients in Energy Expenditure

Frontiers in Endocrinology, 2017
Animals store metabolic energy as electrochemical gradients. At least 50% of mammalian energy is expended to maintain electrochemical gradients across the inner mitochondrial membrane (H+), the sarcoplasmic reticulum (Ca++), and the plasma membrane (Na ...
Caroline E. Geisler, Kyle P. Kentch, Benjamin J. Renquist   +2 more
doaj   +1 more source

Apocytochrome c [PDF]

, 1990
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout, Böhni, Chen, Cheng, Chirico, Daldal, Deshaies, Deshaies, Drygas, Dumont, Dumont, Eilers, Enosawa, Gabellini, Gabellini, Gasser, Hartl, Hartl, Hawlitschek, Hennig, Hennig, Hennig, Horwich, Horwich, Hurt, Hurt, Jordi, Korb, Lewis, Matsuura, McAda, Meyer, Nargang, Nicholson, Nicholson, Nicholson, Nicholson, Pelham, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pollock, Randall, Rietveld, Rietveld, Rietveld, Rietveld, Rietveld, Rothman, Römisch, Sadler, Schleyer, Schleyer, Schwaiger, Smith, Stewart, Stuart, Stuart, Söllner, Teintze, Welch, Zimmermann, Zimmermann, Zitomer, Zwizinski, Zwizinski   +68 more
core   +1 more source

Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease

Marine Drugs, 2017
Meretrix meretrix oligopeptides (MMO) derived from shellfish have important medicinal properties. We previously obtained MMO from alcalase by hydrolysis processes.
Fangfang Huang, Shasha Zhao, Fangmiao Yu, Zuisu Yang, Guofang Ding   +4 more
doaj   +1 more source

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, Neupert, Walter, Schwaiger, Martin   +2 more
core   +3 more sources