Results 41 to 50 of about 704,132 (300)
Mitochondrial membrane potential in cardiac myocytes
Physiological Research, 2002 Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield ...
L, Skárka, B, Ostádal
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Journal of Ovarian Research, 2021 Mitochondrial injury in granulosa cells (GCs) is associated with the pathophysiological mechanism of polycystic ovary syndrome (PCOS). Melatonin reduces the mitochondrial injury by enhancing SIRT1 (NAD-dependent deacetylase sirtuin-1), while the ...
Bo Zheng +5 more
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Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis [PDF]
, 2015 Muscle dysfunction is a common feature of severe sepsis and multi-organ failure. Recent evidence implicates bioenergetic dysfunction and oxidative damage as important underlying pathophysiological mechanisms.
Brown GC +11 more
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Mitochondrial Membrane Potential in Aging Cells
Neurosignals, 2001 Decreased mitochondrial membrane potential (DeltaPsi(M)) has been found in a variety of aging cell types from several mammalian species. The physiological significance and mechanisms of the decreased DeltaPsi(M) in aging are not well understood. This review considers the generation of DeltaPsi(M) and its role in ATP generation together with factors ...
M M, Sugrue, W G, Tatton
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In vivo quantification of mitochondrial membrane potential
Nature, 2020 Momcilovic et al1 report mitochondrial metabolism differences amongst various mouse lung cancer subtypes, as measured by positron emission tomography (PET) and a voltage-sensitive tracer. They describe their experiments as measurements of mitochondrial membrane potential, ΔΨm, and suggest that they might be used as a non-invasive biomarker to guide the
Nathaniel M. Alpert +4 more
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Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
, 2017 Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
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Mitotracker probes and mitochondrial membrane potential [PDF]
Shock, 2013 In the recent article by Lin et al. (1), the authors demonstrate protective effects of splenic infusion of isolated mitochondria against hepatic ischemia/reperfusion injury in a rat model. One of their conclusions is that the isolated mitochondria from donor animals maintained an intact membrane potential in the livers of recipient animals even at 4 ...
Han-Chen Lin, I-Rue Lai
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Frontiers in Physiology, 2018 Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single ...
Alexis R. Díaz-Vegas +12 more
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Antioxidants, 2022 Recent studies have related mitochondrial impairment with peritoneal membrane damage during peritoneal dialysis (PD) therapy. Here, we assessed the involvement of mitochondrial dysfunction in the inflammatory response in human mesothelial cells, a ...
Olalla Ramil-Gómez +7 more
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Adenine Nucleotide Translocase 1 Expression is Coupled to the HSP27-Mediated TLR4 Signaling in Cardiomyocytes [PDF]
, 2019 The cardiac-specific overexpression of the adenine nucleotide translocase 1 (ANT1) has cardioprotective effects in various experimental heart disease models.
Dörner, Andrea +6 more
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