Results 11 to 20 of about 4,850,535 (301)
Transport of proteins across mitochondrial membranes [PDF]
The Clinical Investigator, 1994 The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes of the mitochondrion without interfering with the integrity or functions of the organelle.
Neupert, Walter
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Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters [PDF]
Journal of Biological Chemistry, 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Although
Adrian Taylor +3 more
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Identification of a Membrane Protein Involved in Mitochondrial Phosphate Transport [PDF]
European Journal of Biochemistry, 1976 A specific labeling by radioactive N‐ethylmaleimide of a protein involved in phosphate transport was obtained by protecting one of the two ‐SH groups of the transport system with low concentrations of mersalyl. Subsequently, the other free ‐SH groups were blocked with excess N‐ethylmaleimide.
P, Hadvary, B, Kadenbach
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Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert +5 more
core +2 more sources
Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]
, 1987 Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker +5 more
core +2 more sources
Dual Role of Mitochondrial Porin in Metabolite Transport across the Outer Membrane and Protein Transfer to the Inner Membrane [PDF]
Molecular Cell, 2019 The mitochondrial inner membrane harbors a large number of metabolite carriers. The precursors of carrier proteins are synthesized in the cytosol and imported into mitochondria by the translocase of the outer membrane (TOM) and the carrier translocase of the inner membrane (TIM22). Molecular chaperones in the cytosol and intermembrane space bind to the
Ellenrieder, Lars +7 more
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Transport of proteins into mitochondria [PDF]
, 1985 Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core +1 more source
Uniform nomenclature for the protein transport machinery of the mitochondrial membranes
Trends in Biochemical Sciences, 1996 [no abstract avaiable]
Pfanner, N. +9 more
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Journal of Lipid Research, 2012 Mitochondrial cholesterol is maintained within a narrow range to regulate steroid and oxysterol synthesis and to ensure mitochondrial function. Mitochondria acquire cholesterol through several pathways from different cellular pools.
Barry E. Kennedy +2 more
doaj +1 more source
Contact, 2023 Numerous studies have revealed that organelle membrane contact sites (MCSs) play important roles in diverse cellular events, including the transport of lipids and ions between connected organelles.
Shintaro Fujimoto +2 more
doaj +1 more source