Results 21 to 30 of about 4,850,535 (301)

Formation and Regulation of Mitochondrial Membranes

International Journal of Cell Biology, 2014
Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the activity of respiratory proteins, and the transport of proteins into the mitochondria.
Laila Cigana Schenkel, Marica Bakovic
doaj   +1 more source

MOM19, an import receptor for mitochondrial precursor proteins [PDF]

, 1989
We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Söllner, Thomas, Pfaller, Rupert, Pfanner, Nikolaus, Neupert, Walter, Griffiths, Gareth   +4 more
core   +1 more source

Miro proteins and their role in mitochondrial transfer in cancer and beyond

Frontiers in Cell and Developmental Biology, 2022
Mitochondria are organelles essential for tumor cell proliferation and metastasis. Although their main cellular function, generation of energy in the form of ATP is dispensable for cancer cells, their capability to drive their adaptation to stress ...
Zuzana Nahacka, Jaromir Novak, Jaromir Novak, Renata Zobalova, Jiri Neuzil, Jiri Neuzil   +5 more
doaj   +1 more source

Proteins and lipids of glycosomal membranes from Leishmania tarentolae and Trypanosoma brucei [v1; ref status: indexed, http://f1000r.es/x1]

F1000Research, 2013
In kinetoplastid protists, several metabolic pathways, including glycolysis and purine salvage, are located in glycosomes, which are microbodies that are evolutionarily related to peroxisomes.
Claudia Colasante, Frank Voncken, Theresa Manful, Thomas Ruppert, Aloysius G M Tielens, Jaap J van Hellemond, Christine Clayton   +6 more
doaj   +1 more source

Protein transport machineries for precursor translocation across the inner mitochondrial membrane

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
The mitochondrial inner membrane has a central function for the energy metabolism of the cell. The respiratory chain generates a proton gradient across the inner mitochondrial membrane, which is used to produce ATP by the F1Fo-ATPase. To maintain the electrochemical gradient, the inner membrane represents an efficient permeability barrier for small ...
Wagner, Karina, Mick, David U., Rehling, Peter   +2 more
openaire   +3 more sources

Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria

BMC Biology, 2018
Background Bacteria and mitochondria contain translocases that function to transport proteins across or insert proteins into their inner and outer membranes. Extant mitochondria retain some bacterial-derived translocases but have lost others.
Markéta Petrů, Jeremy Wideman, Kristoffer Moore, Felicity Alcock, Tracy Palmer, Pavel Doležal   +5 more
doaj   +1 more source

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ida J. van der Klei, Walter Neupert, Neupert, Walter, Marten Veenhuis, Veenhuis, Marten, Klei, Ida J. van der   +5 more
core   +1 more source

The plant mitochondrial carrier family: functional and evolutionary aspects

Frontiers in Plant Science, 2012
Mitochondria play a key role in respiration and energy production and are involved in multiple eukaryotic but also in several plant specific metabolic pathways. Solute carriers in the inner mitochondrial membrane connect the internal metabolism with that
Ilka eHaferkamp, Stephan eSchmitz-Esser
doaj   +1 more source

Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis [PDF]

, 2009
The bacterial PorB porin, an ATP-binding beta-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial
Kepp, Oliver, Meinecke, M., Harsman, Anke, Meinecke, Michael, Joachim Rassow, Hauf, Eva, Kepp, O., Günther, Dirk, Oliver Kepp, Richard Wagner, Dirk Günther, Thomas Rudel, Hauf, E., Wagner, R., Katharina Ross, Rassow, Joachim, Volker Brinkmann, Brinkmann, Volker, Rajalingam, Krishnaraj, Ines Herrmann, Elke A. Dian-Lothrop, Brinkmann, V., Kozjak-Pavlovic, V., Günther, D., Kozjak-Pavlovic, Vera, Ross, Katharina, Eva Hauf, Vera Kozjak-Pavlovic, Michael Meinecke, Robert Hurwitz, Dian-Lothrop, E., Wagner, Richard, Ross, K., Rajalingam, K., Rudel, T., Dian-Lothrop, Elke A., Rudel, Thomas, Hurwitz, Robert, Krishnaraj Rajalingam, Harsman, A., Elke A Dian-Lothrop, Herrmann, I., Hurwitz, R., Herrmann, Ines, Rassow, J., Anke Harsman   +45 more
core   +2 more sources

Successive translocation into and out of the mitochondrial matrix [PDF]

, 1987
We investigated the import and sorting pathways of cytochrome b2 and cytochrome c1, which are functionally located in the intermembrane space of mitochondria.
Ostermann, Joachim, Hartl, Franz-Ulrich, Neupert, Walter, Guiard, Bernard   +3 more
core   +1 more source