Results 31 to 40 of about 4,850,535 (301)
NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes
Biomolecules, 2023 The mitochondrial pyruvate carrier (Mpc) plays an indispensable role in the transport of pyruvates across the mitochondrial inner membrane. Despite the two distinct homologous proteins, Mpc1 and Mpc2, were identified in 2012, there are still ...
Zhen Wang +8 more
doaj +1 more source
Early steps in mitochondrial protein import [PDF]
, 1990 The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Stuart, Rosemary A. +2 more
core +1 more source
Import pathways of precursor proteins into mitochondria [PDF]
, 1988 The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert +4 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Mitochondria are double-membrane organelles that contain their own genome, the mitochondrial DNA (mtDNA), and reminiscent of its endosymbiotic origin.
Stefan Geldon +2 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1998 Immobilized calcium affinity chromatography was used to obtain a preparation enriched in calcium transporters from Triton X-100 extracts of rat liver mitochondria inner membranes (PPCT). The PPCT were reconstituted into preformed asolectin liposomes which contained 120 mM KCl as internal high K+ medium.
Villa, Ana +5 more
openaire +2 more sources
Transport of proteins to the mitochondrial intermembrane space: the ‘sorting’ domain of the cytochrome c1 presequence is a stop‐transfer sequence specific for the mitochondrial inner membrane. [PDF]
The EMBO Journal, 1987 The presequence of yeast cytochrome c1 (an inner membrane protein protruding into the intermembrane space) contains a matrix-targeting domain and an intramitochondrial sorting domain. This presequence transports attached subunit IV of cytochrome c oxidase into the intermembrane space (van Loon et al. (1987) EMBO J., 6, 2433-2439). In order to determine
A P, van Loon, G, Schatz
openaire +2 more sources
Mitochondrial protein import [PDF]
, 1988 Transport of nuclear-encoded precursor proteins into mitochondria includes proteolytic cleavage of aminoterminal targeting sequences in the mitochondrial matrix. We have isolated the processing activity from Neurospora crassa.
Hawlitschek, Gerhard +5 more
core +1 more source
Mitochondrial Quality Control Governed by Ubiquitin
Frontiers in Cell and Developmental Biology, 2020 Mitochondria are essential organelles important for energy production, proliferation, and cell death. Biogenesis, homeostasis, and degradation of this organelle are tightly controlled to match cellular needs and counteract chronic stress conditions ...
Sonia Ravanelli +3 more
doaj +1 more source
A mitochondrial import receptor for the ADP/ATP carrier [PDF]
, 1990 We have identified a mitochondrial outer membrane protein of 72 kd (MOM72) that exhibits the properties of an import receptor for the ADP/ATP carrier (AAC), the most abundant mitochondrial protein.
Söllner, Thomas +4 more
core +1 more source
eLife, 2016 The TIM22 complex mediates the import of hydrophobic carrier proteins into the mitochondrial inner membrane. While the TIM22 machinery has been well characterised in yeast, the human complex remains poorly characterised. Here, we identify Tim29 (C19orf52)
Yilin Kang +9 more
doaj +1 more source