Results 11 to 20 of about 273,415 (305)

Effect of F16-Betulin Conjugate on Mitochondrial Membranes and Its Role in Cell Death Initiation. [PDF]

Membranes (Basel), 2021
Dubinin MV, Semenova AA, Nedopekina DA, Davletshin EV, Spivak AY, Belosludtsev KN.   +5 more
europepmc   +3 more sources

Mitochondrial Membrane Remodeling [PDF]

Frontiers in Bioengineering and Biotechnology, 2022
Mitochondria are key regulators of many important cellular processes and their dysfunction has been implicated in a large number of human disorders. Importantly, mitochondrial function is tightly linked to their ultrastructure, which possesses an intricate membrane architecture defining specific submitochondrial compartments.
Ziyun Yang, Ziyun Yang, Ziyun Yang, Liang Wang, Cheng Yang, Cheng Yang, Cheng Yang, Shiming Pu, Shiming Pu, Shiming Pu, Ziqi Guo, Ziqi Guo, Ziqi Guo, Qiong Wu, Qiong Wu, Qiong Wu, Zuping Zhou, Zuping Zhou, Zuping Zhou, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao   +22 more
openaire   +5 more sources

Chlamydial membrane vesicles deliver the beta barrel outer membrane protein OmpA to mitochondria to inhibit apoptosis. [PDF]

PLoS Pathogens
Chlamydiae are obligate intracellular bacteria that inhibit mitochondrial apoptosis to maintain integrity of the host cell. We have previously reported that a chlamydial outer membrane β-barrel protein, OmpA, can during ectopic expression inhibit ...
Andreea Mesesan, Henry Oehler, Collins Waguia Kontchou, Aladin Haimovici, Martin Helmstädter, Oliver Kretz, Oliver Schilling, Stefan Tholen, John Atanga, Irina Nazarenko, Ulf Matti, Jonas Ries, Ian E Gentle, Georg Häcker   +13 more
doaj   +2 more sources

Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis

Cell Death and Disease, 2022
The recruitment of DRP1 to mitochondrial membranes prior to fission is facilitated by the wrapping of endoplasmic reticulum (ER) membranes around the mitochondria.
Rachel J. Carter, Mateus Milani, Alison J. Beckett, Shiyu Liu, Ian A. Prior, Gerald M. Cohen, Shankar Varadarajan   +6 more
doaj   +1 more source

Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

Life Science Alliance, 2022
This study shows that lipids can act as regulators for the ubiquitination process and can control the stability and activity of a membrane-embedded E3 ubiquitin ligase. Mitochondrial homeostasis is tightly controlled by ubiquitination.
Lisa Merklinger, Johannes Bauer, Per A Pedersen, Rune Busk Damgaard, J Preben Morth   +4 more
doaj   +1 more source

Mitochondrial membrane potential [PDF]

Analytical Biochemistry, 2018
The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III and IV) is an essential component in the process of energy storage during oxidative phosphorylation. Together with the proton gradient (ΔpH), ΔΨm forms the transmembrane potential of hydrogen ions which is harnessed to make ATP.
Ljubava D, Zorova, Vasily A, Popkov, Egor Y, Plotnikov, Denis N, Silachev, Irina B, Pevzner, Stanislovas S, Jankauskas, Valentina A, Babenko, Savva D, Zorov, Anastasia V, Balakireva, Magdalena, Juhaszova, Steven J, Sollott, Dmitry B, Zorov   +11 more
openaire   +2 more sources

Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise. [PDF]

PLoS ONE, 2015
Exercise has been shown to induce the translocation of fatty acid translocase (FAT/CD36), a fatty acid transport protein, to both plasma and mitochondrial membranes.
Cynthia Monaco, Jamie Whitfield, Swati S Jain, Lawrence L Spriet, Arend Bonen, Graham P Holloway   +5 more
doaj   +1 more source

Pathways shaping the mitochondrial inner membrane

Open Biology, 2021
Mitochondria are complex organelles with two membranes. Their architecture is determined by characteristic folds of the inner membrane, termed cristae.
Till Klecker, Benedikt Westermann
doaj   +1 more source

Unraveling the Role of Drug-Lipid Interactions in NSAIDs-Induced Cardiotoxicity

Membranes, 2020
Cardiovascular (CV) toxicity is nowadays recognized as a class effect of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs). However, their mechanisms of cardiotoxicity are not yet well understood, since different compounds with similar action ...
Catarina Pereira-Leite, Marina Figueiredo, Kinga Burdach, Cláudia Nunes, Salette Reis   +4 more
doaj   +1 more source

Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties

Frontiers in Molecular Biosciences, 2022
The mitochondrion is an essential organelle enclosed by two membranes whose functionalities depend on their very specific protein and lipid compositions.
Olivia Schiaffarino, David Valdivieso González, David Valdivieso González, Inés M. García-Pérez, Daniel A. Peñalva, Daniel A. Peñalva, Víctor G. Almendro-Vedia, Víctor G. Almendro-Vedia, Paolo Natale, Paolo Natale, Iván López-Montero, Iván López-Montero, Iván López-Montero   +12 more
doaj   +1 more source