The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration [PDF]
Nature Communications, 2019 Induction of mitochondrial oxidative respiration is required for stem cell differentiation, but the mechanisms underlying this process are poorly understood.
David Sala +9 more
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Menstrual cycle influence on skeletal muscle mitochondrial respiration in humans [PDF]
Physiological ReportsThe menstrual cycle influences function in various tissues in the body. We sought to determine if menstrual cycle phase could influence mitochondrial function in skeletal muscle in females.
W. Bradley Nelson +10 more
doaj +2 more sources
A novel extracellular flux assay workflow uncovers impaired sciatic nerve mitochondrial respiration in diabetic db/db mice [PDF]
Cell Communication and SignalingAbnormal mitochondrial function contributes to the development of diabetic neuropathy by inducing oxidative stress and altering energy metabolism, ultimately leading to neuronal damage.
Sebastian Sill +9 more
doaj +2 more sources
How to Measure Mitochondrial Oxygen Respiration [PDF]
운동과학, 2023 PURPOSE With the widespread of mitochondrial function, the need to accurately quantify and comprehend mitochondrial O2 respiration has gained prominence within the physiological and pathological spheres.
Jun-Won Heo +7 more
doaj +1 more source
Frontiers in Physiology, 2023 Introduction: Mitochondrial dysfunction is linked to a variety of human diseases. Understanding the dynamic alterations in mitochondrial respiration at various stages of development is important to our understanding of disease progression.
Bridget Konadu +4 more
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Age-Dependent Alterations in Platelet Mitochondrial Respiration
Biomedicines, 2023 Mitochondrial dysfunction is an important cellular hallmark of aging and neurodegeneration. Platelets are a useful model to study the systemic manifestations of mitochondrial dysfunction.
Zdeněk Fišar +5 more
doaj +1 more source
Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function. [PDF]
PLoS ONE, 2014 The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis ...
Fredrik Sjövall +4 more
doaj +3 more sources
Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
Molecular Metabolism, 2022 Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer +8 more
doaj +1 more source
Scientific Reports, 2023 A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes mitochondrial respiration and attenuates mitochondrial oxidative stress in cultured cardiomyocytes.
Kirsten T. Nijholt +10 more
doaj +1 more source
Invasive and noninvasive markers of human skeletal muscle mitochondrial function
Physiological Reports, 2023 Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninvasive markers ...
Rodrigo Mancilla +10 more
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