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Control of mitochondrial respiration [PDF]

open access: yesFEBS Letters, 1983
The control theory of Kacser and Burns [in: Rate Control of Biological Processes (Davies, D.D. ed) pp. 65–104, Cambridge University Press, London, 1973] and Heinrich and Rapoport ([Eur. J. Biochem. (1974) 42, 97‐105] has been used to quantify the amount of control exerted by different steps on mitochondrial oxidative phosphorylation in rat‐liver ...
Tager, J.M.   +9 more
  +8 more sources

Analysis of oxygen consumption rates in zebrafish reveals differences based on sex, age and physical activity recovery

open access: yesFrontiers in Physiology, 2023
Introduction: Mitochondrial dysfunction is linked to a variety of human diseases. Understanding the dynamic alterations in mitochondrial respiration at various stages of development is important to our understanding of disease progression.
Bridget Konadu   +4 more
doaj   +1 more source

Age-Dependent Alterations in Platelet Mitochondrial Respiration

open access: yesBiomedicines, 2023
Mitochondrial dysfunction is an important cellular hallmark of aging and neurodegeneration. Platelets are a useful model to study the systemic manifestations of mitochondrial dysfunction.
Zdeněk Fišar   +5 more
doaj   +1 more source

How to Measure Mitochondrial Oxygen Respiration [PDF]

open access: yes운동과학, 2023
PURPOSE With the widespread of mitochondrial function, the need to accurately quantify and comprehend mitochondrial O2 respiration has gained prominence within the physiological and pathological spheres.
Jun-Won Heo   +7 more
doaj   +1 more source

Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function. [PDF]

open access: yesPLoS ONE, 2014
The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis ...
Fredrik Sjövall   +4 more
doaj   +3 more sources

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

open access: yesMolecular Metabolism, 2022
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer   +8 more
doaj   +1 more source

A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise

open access: yesScientific Reports, 2023
A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes mitochondrial respiration and attenuates mitochondrial oxidative stress in cultured cardiomyocytes.
Kirsten T. Nijholt   +10 more
doaj   +1 more source

Invasive and noninvasive markers of human skeletal muscle mitochondrial function

open access: yesPhysiological Reports, 2023
Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninvasive markers ...
Rodrigo Mancilla   +10 more
doaj   +1 more source

Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. [PDF]

open access: yesPLoS ONE, 2012
During sepsis, liver dysfunction is common, and failure of mitochondria to effectively couple oxygen consumption with energy production has been described.
Siamak Djafarzadeh   +3 more
doaj   +1 more source

Protocol for Measurement of Oxygen Consumption Rate In Situ in Permeabilized Cardiomyocytes

open access: yesSTAR Protocols, 2020
Summary: Analysis of mitochondrial respiration function represented by the oxygen consumption rate is necessary for assessing mitochondrial respiration function.
Meng Gao   +4 more
doaj   +1 more source

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