Results 271 to 280 of about 1,557,014 (330)
Reversible and irreversible mitochondrial swelling in vitro.
Biophysical Chemistry, 2021 Mitochondrial activity as regards ATP production strongly depends on mitochondrial swelling (MS) mode. Therefore, this work analyzes reversible and irreversible MS using a detailed biophysical model. The reported model includes mechanical properties of the inner mitochondrial membrane (IMM).
I. Khmelinskii, V. Makarov
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Mitochondrial Swelling Induced by Glutathione [PDF]
The Journal of Biophysical and Biochemical Cytology, 1959 Reduced glutathione, in concentrations approximating those occurring in intact rat liver, causes swelling of rat liver mitochondria in vitro which is different in kinetics and extent from that yielded by L-thyroxine. The effect is also given by cysteine, which is more active, and reduced coenzyme A, but not by L-ascorbate, cystine, or oxidized ...
A L Lehninger, Albert L. Lehninger
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Experimental Physiology, 2013 The meaning of cholesterol pool reduction in heart mitochondria after exercise is still unknown phenomenon. Therefore, the aim of the study was to establish whether the decreased cholesterol content in heart mitochondria caused by prolonged swimming may ...
W. Ziółkowski +10 more
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SIAM Journal on Mathematical Analysis, 2020
The model that we investigate here is motivated by the mitochondrial swelling process controlled by calcium ions, the spatial dynamics of which is described by degenerate diffusion.
M. Efendiev, M. Otani, H. Eberl
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The model that we investigate here is motivated by the mitochondrial swelling process controlled by calcium ions, the spatial dynamics of which is described by degenerate diffusion.
M. Efendiev, M. Otani, H. Eberl
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Inhibition of brain mitochondrial swelling by idebenone
Archives of Gerontology and Geriatrics, 1989The effects of idebenone on the swelling of rat brain mitochondria were studied. When FeCl3 was added to a mitochondrial suspension, a pronounced mitochondrial swelling occurred accompanied by the production of lipid peroxide; the two phenomena were closely correlated (r = 0.96, p less than 0.01).
Akinobu Nagaoka, M Suno, A Nagaoka
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Differentiation of types of mitochondrial swelling
Experimental and Molecular Pathology, 1962Abstract Transformations of rat liver mitochondria were studied under metabolizing and nonmetabolizing conditions. The transformations were followed simultaneously by three methods: (1) Measurement of absorbancy changes at 520 mμ; (2) mitocrit (packed volume) measurements; and (3) evaluation of morphological alterations by phase contrast microscopy.
J W, HARMAN, M T, O'HEGARTY
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Journal of biochemical and molecular toxicology, 2018
Brain tissue manganese (Mn) accumulation is a cirrhosis‐associated complication. Cellular mitochondria are among the potential targets for Mn‐induced cytotoxicity.
N. Ahmadi +4 more
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Brain tissue manganese (Mn) accumulation is a cirrhosis‐associated complication. Cellular mitochondria are among the potential targets for Mn‐induced cytotoxicity.
N. Ahmadi +4 more
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Reversible and irreversible mitochondrial swelling: Effects of variable mitochondrial activity
Biosystems, 2021An extended biophysical model was obtained by upgrading the previously reported one (Khmelinskii and Makarov, 2021). The upgraded model accommodates variations of solute transport rates through the inner mitochondrial membrane (IMM) within the mitochondrial population, described by a Gaussian distribution.
Igor Khmelinskii, Vladimir I. Makarov
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Osmotic reversal of mitochondrial swelling
Biochimica et Biophysica Acta, 1961Previously published data1,11 have been found consistent with the hypothesis that mitochodrial swelling is primarily the result of the penetration of the suspending solute. A relaxation of a contractile mechanism or the hydration of an internal gel-like material do not seem to be significant in this process.
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