Results 301 to 310 of about 96,831 (392)

Mitophagy: Growing in Intricacy [PDF]

Autophagy, 2007
openaire   +2 more sources

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies  (Review). [PDF]

Mol Med Rep
Chen Y, Zhang Z, Zhou G.
europepmc   +1 more source

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

The FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut, Danae Campos‐Melo, Michael J. Strong   +2 more
wiley   +1 more source

Mitochondrial Dysfunction Combined with Elevated CoQ₁₀ Levels Specifically in Placental Cytotrophoblasts Suggests a Role for Mitophagy in Preeclampsia. [PDF]

Biology (Basel)
Ábalos-Martínez J, Visiedo F, Cascajo-Almenara MV, Santos-Rosendo C, Melero-Jiménez V, Santos-Ocaña C, Vázquez-Fonseca L, Bugatto F.   +7 more
europepmc   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

Mitochondrial quality control mechanisms as molecular targets for impaired lung development: from fetuses to neonates. [PDF]

Respir Res
Zhu Z, Zhang L, Fu J.
europepmc   +1 more source

Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia

, 2016
Aimin Qiao, Kuansong Wang, Yunsheng Yuan, Yidi Guan, Xingcong Ren, Lanya Li, Xisha Chen, Li Feng, Alex F. Chen, Jianda Zhou, Jinming Yang, Yan Cheng   +11 more
openalex   +2 more sources

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

PINK1/PARKIN-mediated Mitophagy: Friend or Foe in Hypoxia-induced Pulmonary Vascular Remodeling? [PDF]

Am J Respir Cell Mol Biol
Pak O, Sommer N.
europepmc   +1 more source