Results 311 to 320 of about 96,831 (392)

Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway

, 2019
Fei Yin, Jun Yan, Yue Zhao, Ke-Jun Guo, Zhili Zhang, Anpei Li, Chunyang Meng, Li Guo   +7 more
openalex   +1 more source

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source

TGM2-P2RX7 loop promotes gemcitabine resistance in pancreatic cancer by modulating glutamine metabolism and mitophagy. [PDF]

Cell Death Discov
Ye K, Zhou S, Gong X, Zhu Z, Xiao M, Liang S.   +5 more
europepmc   +1 more source

Natural small molecules regulating the mitophagy pathway counteract the pathogenesis of diabetes and chronic complications [PDF]

Ye Du, Junping Zhu, Shengrui Su, Yunfeng Yu, Jun Zhang, Yuman Yin, Chuanquan Lin, Xue‐Jiao Xie, Xiang Qin, Rong Yu   +9 more
openalex   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

HIF1α Attenuated the Lung Ischemia-Reperfusion Injury by Activating the miR-485/Notch1 Signalling. [PDF]

J Cell Mol Med
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J.   +6 more
europepmc   +1 more source

Abnormal Glucose Metabolism in Alzheimer’s Disease: Relation to Autophagy/Mitophagy and Therapeutic Approaches

, 2015
Kalpita Banerjee, Soumyabrata Munshi, David E. Frank, Gary E. Gibson   +3 more
openalex   +2 more sources

Exercise training to preserve vitality capacity in ageing

Experimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford   +12 more
wiley   +1 more source

Global trends and perspectives in mitophagy on neurodegenerative diseases: a scientometric analysis over 20 years. [PDF]

Front Med (Lausanne)
Wu H, Zhang M, Zhang L, Liu H, Fan H.
europepmc   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source