Results 331 to 340 of about 96,831 (392)

TRPC6-Calpain-1 Axis Promotes Tubulointerstitial Inflammation by Inhibiting Mitophagy in Diabetic Kidney Disease

Congcong Liu, Jialing Ji, Ze Wang, Xing-Jian Zhang, Lin Ding, Yao Zhang, Yan Zhou, Dongjie Zhang, Zhen-Lin Tang, Jingyuan Cao, Aiqing Zhang, Bi‐Cheng Liu, Zuo‐Lin Li, Ruixia Ma   +13 more
openalex   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
wiley   +1 more source

Enriched Environment Ameliorates Cerebral Ischemia-Reperfusion Injury via Dopamine-H₂S Axis-Mediated Dual Mitophagy Activation. [PDF]

Antioxidants (Basel)
Zhou B, Qin H, Yang P, Ren N, Sun L, Ding Z, He Z, Zhang S, Hua Z, Zheng Y, Li C, Kuang S, Zhu Y, Yu K.   +13 more
europepmc   +1 more source

Impact of combined ginsenoside‐MC1 and irisin on mitochondrial apoptosis in diabetic rats with hepatic reperfusion injury: Role of AMPK/JNK signalling

Experimental Physiology, EarlyView.
Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin, Lei Han, Zhigang Ma, Bo Yuan, Yabin Yu   +4 more
wiley   +1 more source

Intestinal γδ T17-IL-17A signaling disrupts hippocampal mitophagy in stress-induced depression and is restored by arketamine. [PDF]

J Neuroinflammation
Han M, Xie B, Yu Y, Xu D, Shi Y, Xu M, Wu Y, Zhang Y, Wen X, Wang X, Zhen Z, Zhang X, Sun X, Yuan Y, Shang Y, Yuan S, Hashimoto K, Zhang J.   +17 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Exercise regulates mitophagy to alleviate parkinsonian neurodegeneration. [PDF]

Front Aging Neurosci
Liu C, He W, Zhang J.
europepmc   +1 more source

Mitochondrial capacities and quality control following short‐ and long‐term weight restoration after simulated anorexia nervosa

Experimental Physiology, EarlyView.
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell, Toby L. Chambers, Lauren Breithaupt, Ruqaiza Muhyudin, Patience Salvalina Okoto, Sadie R. Thompson, Emily E. Rothacker, Claire Greenhill, Katie A. Wood, Kevin A. Murach, Sarah H. White‐Springer, Ursula B. Kaiser, Seward B. Rutkove   +12 more
wiley   +1 more source

Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy. [PDF]

Biochem Biophys Rep
Ma C, Gai W, Zhang K, Qin C.
europepmc   +1 more source

Enoxaparin preserves cellular morphology and modulates mitophagy-associated Parkin–LC3 in acute ischemic rat myocardium

Fevzi Ayyıldız, Uğur Karagöz, Tünay Kurtoğlu, Pınar Akokay, Çağatay Bilen   +4 more
openalex   +1 more source