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Biochimica et Biophysica Acta (BBA) - General Subjects, 2021
Mitochondria play a central role in primary metabolism in plants as well as in heterotrophic eukaryotes. Plants must control the quality and number of mitochondria in response to a changing environment, across cell types and developmental stages. Mitophagy is defined as the degradation of mitochondria by autophagy, an evolutionarily conserved system ...
Sakuya, Nakamura +2 more
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Mitochondria play a central role in primary metabolism in plants as well as in heterotrophic eukaryotes. Plants must control the quality and number of mitochondria in response to a changing environment, across cell types and developmental stages. Mitophagy is defined as the degradation of mitochondria by autophagy, an evolutionarily conserved system ...
Sakuya, Nakamura +2 more
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Yeast mitophagy: Unanswered questions
Biochimica et Biophysica Acta (BBA) - General Subjects, 2021Superfluous and damaged mitochondria need to be efficiently repaired or removed. Mitophagy is a selective type of autophagy that can engulf a portion of mitochondria within a double-membrane structure, called a mitophagosome, and deliver it to the vacuole for degradation. Mitophagy has significant physiological functions from yeast to human, and recent
Yuxiang J, Huang, Daniel J, Klionsky
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The International Journal of Biochemistry & Cell Biology, 2014
Eukaryotes employ elaborate mitochondrial quality control to maintain the function of the power-generating organelle. Mitochondrial quality control is particularly important for the maintenance of neural and muscular tissues. Mitophagy is specialized version of the autophagy pathway. Mitophagy delivers damaged mitochondria to lysosomes for degradation.
Nobutaka, Hattori +2 more
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Eukaryotes employ elaborate mitochondrial quality control to maintain the function of the power-generating organelle. Mitochondrial quality control is particularly important for the maintenance of neural and muscular tissues. Mitophagy is specialized version of the autophagy pathway. Mitophagy delivers damaged mitochondria to lysosomes for degradation.
Nobutaka, Hattori +2 more
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Essays in Biochemistry, 2013
Mitophagy describes the selective targeting and degradation of mitochondria by the autophagy pathway. In this process, defective mitochondria are first purged from the mitochondrial network then delivered to the lysosome by the autophagy machinery.
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Mitophagy describes the selective targeting and degradation of mitochondria by the autophagy pathway. In this process, defective mitochondria are first purged from the mitochondrial network then delivered to the lysosome by the autophagy machinery.
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Biochemistry (Moscow), 2019
Mitochondria play a crucial role in energy production, general cell metabolism, cell signaling, and apoptosis. Mitochondria are also the main source of reactive oxygen species, especially in the case of their dysfunction. Therefore, damaged or even superfluous mitochondria not required for normal cell functioning represent risk factors and should be ...
D V, Mamaev, R A, Zvyagilskaya
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Mitochondria play a crucial role in energy production, general cell metabolism, cell signaling, and apoptosis. Mitochondria are also the main source of reactive oxygen species, especially in the case of their dysfunction. Therefore, damaged or even superfluous mitochondria not required for normal cell functioning represent risk factors and should be ...
D V, Mamaev, R A, Zvyagilskaya
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The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy
Autophagy, 2023Mitophagy is a form of autophagy that plays a key role in maintaining the homeostasis of functional mitochondria in the cell. Viruses have evolved various strategies to manipulate mitophagy to escape host immune responses and promote virus replication ...
Bo Zhang +7 more
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Analytical Chemistry, 2023
Mitophagy is a vital cellular process playing vital roles in regulating cellular metabolism and mitochondrial quality control. Mitochondrial viscosity is a key microenvironmental index, closely associated with mitochondrial status.
Jiaxin Hong +5 more
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Mitophagy is a vital cellular process playing vital roles in regulating cellular metabolism and mitochondrial quality control. Mitochondrial viscosity is a key microenvironmental index, closely associated with mitochondrial status.
Jiaxin Hong +5 more
semanticscholar +1 more source
Excessive mitophagy for anxiety
Neuron, 2021In this issue of Neuron, Duan et al. (2021) identified excessive mitophagy in BLA neurons synapsing onto adBNST neurons as a mechanism for reduced neurotransmission and social defeat-induced anxiety-like behaviors.
Hongsheng, Wang +2 more
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Mitophagy in cardiovascular disease
Clinica Chimica Acta, 2020Cardiovascular disease (CVD) leads to high morbidity and mortality rates worldwide. Accumulating evidence has revealed that mitochondria dysfunction is implicated in CVD, such as atherosclerosis (AS), hypertension, myocardial ischemia-reperfusion (MI/R) injury, myocardial infarction (MI), cardiac hypertrophy, heart failure (HF), dilated cardiomyopathy (
Hong Zhou +3 more
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Mitophagy and Mitochondrial Balance
2014Mitochondria are highly dynamic organelles, with a morphology ranging from small roundish elements to large interconnected networks. This fine architecture has a significant impact on mitochondrial homeostasis, and mitochondrial morphology is highly connected to specific cellular process.
PATERGNANI, Simone, PINTON, Paolo
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