Results 361 to 370 of about 96,831 (392)

Targeting mitochondria by lipid-selenium conjugate drug results in malate/fumarate exhaustion and induces mitophagy-mediated necroptosis suppression

International Journal on Biological Sciences
Atherosclerosis (AS) is a chronic vascular disease primarily affecting large and medium-sized arteries and involves various complex pathological mechanisms and factors.
Xing Chang, Hao Zhou, Jinlin Hu, Teng Ge, Kunyang He, Ye Chen, Rongjun Zou, Xiaoping Fan   +7 more
semanticscholar   +1 more source

Mitophagy in Yeast: A Screen of Mitophagy-Deficient Mutants

2017
Mitochondrial autophagy (mitophagy) is a process that selectively degrades mitochondria via autophagy. Recent studies have shown that mitophagy plays an important role in mitochondrial homeostasis by degrading damaged or excess mitochondria. The budding yeast Saccharomyces cerevisiae is a powerful model organism that has been employed to study several ...
Kentaro, Furukawa, Tomotake, Kanki
openaire   +2 more sources

Alternative macroautophagy and mitophagy

The International Journal of Biochemistry & Cell Biology, 2014
Mitophagy is a mitochondrial quality control mechanism where damaged and surplus mitochondria are removed by macroautophagy. Mitophagy is associated with various physiological and pathological events such as mitochondrial clearance during terminal differentiation of reticulocytes.
Shigeomi, Shimizu, Shinya, Honda, Satoko, Arakawa, Hirofumi, Yamaguchi   +3 more
openaire   +2 more sources

Triggering Mitophagy with Photosensitizers

2019
One can utilize light illumination to stimulate mitochondrial reactive oxygen species production through the use of mitochondria-specific photosensitizers. By proper tuning of the light dosage, the methodology permits probing of a multitude of mitochondrial damage responses, including mitophagy. This light-controllable trick offers unique opportunities
Cheng-Wei, Hsieh, Wei Yuan, Yang
openaire   +2 more sources

Mitophagy in human health, ageing and disease

Nature Metabolism, 2023
A. Picca, J. Faitg, Johan Auwerx, L. Ferrucci, Davide D’Amico   +4 more
semanticscholar   +1 more source

Mitophagy

2020
Konstantinos Palikaras, Nektarios Tavernarakis   +1 more
openaire   +1 more source

Involvement of mitochondrial dynamics and mitophagy in diabetic endothelial dysfunction and cardiac microvascular injury

Archives of Toxicology, 2023
Xiao Zhang, Hao Zhou, X. Chang
semanticscholar   +1 more source

Targeting mitophagy in neurodegenerative diseases

Nature reviews. Drug discovery
O. Antico, P. Thompson, Nicholas T Hertz, M. Muqit, Laura E Parton   +4 more
semanticscholar   +1 more source

Mitophagy

2016
Valentina Sica, Valentina Izzo, Jose Manuel Bravo-San Pedro, Naoufal Zamzami, Maria Chiara Maiuri   +4 more
openaire   +1 more source

Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species

Cell Death and Differentiation
S. Yamashita, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Keiichi Inoue, Kentaro Furukawa, Tomoyuki Fukuda, David C. Chan, T. Kanki   +8 more
semanticscholar   +1 more source