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CYP3A4-mediated metabolic conversion of mitragynine to 7-hydroxymitragynine (7OH) has been demonstrated in human liver microsomes, and in rodents. Pharmacokinetics (PK) of mitragynine and 7OH in humans is still limited.
Juraithip Wungsintaweekul +2 more
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Proteomic analysis reveals brain Rab35 as a potential biomarker of mitragynine withdrawal in rats
Brain Research Bulletin, 2021Christian P. Müller +2 more
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The effects of chronic mitragynine (Kratom) exposure on the EEG in rats
Neuroscience Letters, 2021Farah Wahida Suhaimi +2 more
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Mitragynine concentrations in two fatalities
Forensic Science International, 2017Frank Musshoff +2 more
exaly
Development of an ELISA for detection of mitragynine and its metabolites in human urine
Analytical Biochemistry, 2020Surash Ramanathan +2 more
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