Results 171 to 180 of about 2,942 (230)
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Journal of Immunological Methods, 2022
Mitragynine is an alkaloid from Mitragyna speciosa Korth. (kratom), a native tropical plant in Southeast Asia. It could render psychotropic effects and is often misused in substitution for commercial drugs. In recent years, the consumption of kratom has grown rapidly and has led some countries to ban its use.
Mustafa, Radhiahtul Raehan +3 more
openaire +2 more sources
Mitragynine is an alkaloid from Mitragyna speciosa Korth. (kratom), a native tropical plant in Southeast Asia. It could render psychotropic effects and is often misused in substitution for commercial drugs. In recent years, the consumption of kratom has grown rapidly and has led some countries to ban its use.
Mustafa, Radhiahtul Raehan +3 more
openaire +2 more sources
Mitragynine in the Orange County DUID population
Journal of Analytical Toxicology, 2023Abstract In recent years, mitragynine has been consistently detected in driving under the influence of drug (DUID) cases. In this paper, we evaluate 3 years (2017–2019) worth of DUID data from arrested drivers in Orange County, CA, USA.
Nancy Kedzierski, Dani Mata
openaire +2 more sources
Mitragynine and 7-Hydroxymitragynine: Bidirectional Effects on Breathing in Rats
bioRxivThe use of kratom as an alternative to conventional opioids has surged, driven largely by anecdotal reports of its efficacy for pain relief and opioid withdrawal management.
Julio D. Zuarth Gonzalez +6 more
semanticscholar +2 more sources
Mitragynine concentrations in two fatalities
Forensic Science International, 2017Two cases of fatalities are reported of which the recreational use of Mitragyna speciosa ("kratom") could be confirmed. One of these cases presents with one of the highest postmortem mitragynine concentrations published to date. Our results show that even extremely high mitragynine blood concentrations following the consumption of kratom do not ...
Olwen Domingo +6 more
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An accidental poisoning with mitragynine
Forensic Science International, 2014An increasing number of drugs of abuse are sold word wide over the internet. Names like "legal highs", "herbal highs" etc. give the impression that these are safe products, although the risk of fatal reactions might be substantial. Leaves from the plant Mitragyna speciosa, contain active compounds like mitragynine and 7-hydroxymitragynine.
Ritva, Karinen +3 more
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Drug and Alcohol Dependence
BACKGROUND Within the past year, the online sale of semi-synthetic products containing chemicals derived from mitragynine, kratom's primary alkaloid: 7-hydroxymitragynine (7-OH) and mitragynine pseudoindoxyl (MP) has emerged. Both are highly selective mu
M.P.H. Katherine Hill +3 more
semanticscholar +1 more source
BACKGROUND Within the past year, the online sale of semi-synthetic products containing chemicals derived from mitragynine, kratom's primary alkaloid: 7-hydroxymitragynine (7-OH) and mitragynine pseudoindoxyl (MP) has emerged. Both are highly selective mu
M.P.H. Katherine Hill +3 more
semanticscholar +1 more source
Mitragynine improves cognitive performance in morphine-withdrawn rats
Psychopharmacology, 2021The treatment of opiate addiction is an unmet medical need. Repeated exposure to opiates disrupts cognitive performance. Opioid substitution therapy, with, e.g., methadone, may further exacerbate the cognitive deficits. Growing evidence suggests that mitragynine, the primary alkaloid from the Kratom (Mitragyna speciosa) leaves, may serve as a promising
Chiek Yi You +3 more
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Mitragynine (Kratom) ‐ monitoring in sports drug testing
Drug Testing and Analysis, 2016In 2014, mitragynine (Kratom) was placed on the Monitoring List of the World Anti-Doping Agency to gain information of its current use in professional sports. Therefore, analytical strategies in sports drug testing are presented and the first Kratom case in professional sports is described.
Sven, Guddat +4 more
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Kratom pharmacology: Clues from planarians exposed to mitragynine
Physiology & Behavior, 2021Mitragynine (MG), the most prevalent bioactive alkaloid in kratom, displays nanomolar affinity for µ, κ and δ opioid receptors and produces opioid-dependent antinociception and dependence in rats. Here, using a battery of behavioral assays, we investigated MG effects in planarians.
Sarah, Uddin +5 more
openaire +2 more sources
Substance Use & Misuse
Background: Potent semi-synthetic alkaloids that stimulate opioid receptors are being sold to consumers in gas stations, smoke shops, and online as the dietary supplement ‘kratom’.
C. White, Jordyn Belcourt, Ava Sedensky
semanticscholar +1 more source
Background: Potent semi-synthetic alkaloids that stimulate opioid receptors are being sold to consumers in gas stations, smoke shops, and online as the dietary supplement ‘kratom’.
C. White, Jordyn Belcourt, Ava Sedensky
semanticscholar +1 more source