Results 91 to 100 of about 25,228 (245)

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Trisomy 8 in myeloid neoplasms: more than a passenger alteration?

Haematologica
Not available.
Isolde Summerer, Wolfgang Kern
doaj   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms

Haematologica, 2013
Sabine Jeromin, Torsten Haferlach, Vera Grossmann, Tamara Alpermann, Andreas Kowarsch, Claudia Haferlach, Wolfgang Kern, Susanne Schnittger   +7 more
doaj   +1 more source

Dental Caries in Permanent Molars of Children Previously Treated With Silver Fluoride Gel/Sodium Fluoride Varnish in Their Primary Dentition: A Retrospective Cohort Study

International Journal of Paediatric Dentistry, EarlyView.
ABSTRACT Introduction Children with more caries in the primary dentition have been observed to have greater caries risk in the permanent dentition. In a previous trial, we determined lesion arrest in primary teeth, where 38% SDF gel and 2.5% NaF varnish were applied sequentially.
Tania Carola Padilla Cáceres, Jorge Luis Castillo, Claudia Mariela Vera Reyes, Marilynn Rothen, Lloyd L. Mancl, Peter Milgrom   +5 more
wiley   +1 more source

Computed tomography reveals multiple origins of extreme caudal vertebral pneumaticity in sauropod dinosaurs

Journal of Anatomy, EarlyView.
Here, we present novel CT scan data of caudal vertebrae of six Middle–Late Jurassic sauropods, representing several eusauropod lineages. We synthesise these new data with a comprehensive critical appraisal of purported external and internal evidence for caudal vertebral PSP in Sauropodomorpha.
Samantha L. Beeston, Daniela Schwarz, Paul Upchurch, Stephen F. Poropat, Patrick Asbach, Philip D. Mannion   +5 more
wiley   +1 more source

Associations Between Mental Health Conditions and Adverse Pregnancy Outcomes Among Active‐Duty Servicewomen

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Active‐duty servicewomen (ADSW) are at increased risk for mental health conditions compared to civilian women. Research suggests women with mental health conditions experience serious pregnancy complications at rates 50% higher than those without mental health conditions; yet research in military populations is limited. Objective To
Laura L. Manzo, Clinton Hall, Joan Combellick, Ilan Harpaz‐Rotem, Angela K. Phillips, Monica T. Burrell, Chrystelle Kiang, Julie A. Womack   +7 more
wiley   +1 more source

The Association Between Foetal Brain and Body Size Mid‐Gestation and Neurodevelopmental Disorders in Childhood

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Smallness for gestational age and reduced head circumference at birth are consistently associated with later neurodevelopmental disorders (NDD), but it is unclear whether similar associations are present at foetal biometry in mid‐gestation. Objectives To investigate associations between second‐trimester foetal biometric measurements
Mads Langager Larsen, Gorm Greisen, Lone Krebs, Christina Engel Hoei‐Hansen, Olav Bjørn Petersen   +4 more
wiley   +1 more source

Detection and characterization of homozygosity of mutated CALR by copy neutral loss of heterozygosity in myeloproliferative neoplasms among cases with high CALR mutation loads or with progressive disease

Haematologica, 2019
Anna Stengel, Sabine Jeromin, Torsten Haferlach, Manja Meggendorfer, Wolfgang Kern, Claudia Haferlach   +5 more
doaj   +1 more source

P690: IDENTIFICATION OF CLINICALLY RELEVANT VARIANT-LEVEL SEX-BIAS IN SF3B1 K700/K666 AND IDH2 R140/R172

HemaSphere, 2023
Maki Sakuma, Constance Baer, Manja Meggendorfer, Claudia Haferlach, Wolfgang Kern, Torsten Haferlach, Wencke Walter   +6 more
doaj   +1 more source