Results 71 to 80 of about 25,228 (245)

P708: HIGH MUTATIONAL CONCORDANCE IN PAIRED BONE MARROW AND PERIPHERAL BLOOD SAMPLES IN PATIENTS WITH CONFIRMED OR SUSPECTED MYELODYSPLASTIC NEOPLASM

HemaSphere, 2023
Natalie Wossidlo, Sandra Huber, Torsten Haferlach, Manja Meggendorfer, Stephan Hutter, Gregor Hoermann, Isolde Summerer, Henning Ruge, Constance Baer, Wolfgang Kern, Claudia Haferlach   +10 more
doaj   +1 more source

Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia

Molecular Cancer, 2010
Background Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs).
Firth Martin J, Samuels Amy L, Heng Jasmin YS, Palmer Misty-Lee, Rampellini Janelle L, Beesley Alex H, Ford Jette, Kees Ursula R   +7 more
doaj   +1 more source

Alternative seed trait strategies are linked to a trade‐off between spatial and temporal dispersal

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Seed dispersal allows plants to seek favourable conditions or spread the risk of unfavourable conditions through space and time. While theory predicts a trade‐off between spatial and temporal dispersal, empirical tests have been stymied by the difficulty of measuring ...
Marina L. LaForgia, Susan P. Harrison, Michal J. Borton, Pierre‐Olivier Cheptou, Lauren M. Hallett, Jennifer R. Gremer   +5 more
wiley   +1 more source

Detection of ABL1 kinase domain mutations in therapy-naïve BCR-ABL1-positive acute lymphoblastic leukemia

Haematologica, 2021
Constance Baer, Manja Meggendorfer, Claudia Haferlach, Wolfgang Kern, Torsten Haferlach   +4 more
doaj   +1 more source

Automated particle analysis of D.B. Cooper's tie

Journal of Forensic Sciences, EarlyView.
Abstract Automated particle analysis (APA) using scanning electron microscopy (SEM) and energy‐dispersive x‐ray spectrometry (EDS) is a well‐known method in forensics, especially as it is applied to gunshot residue analysis. Here we describe the analysis of particles lifted from D.B. Cooper's tie, which was left on the hijacked plane in 1971.
Thomas G. Kaye, Kent L. Rhodes
wiley   +1 more source

P694: RISK ASSESSMENT ACCORDING TO IPSS-M IS SUPERIOR TO AML ELN 2022 RISK CLASSIFICATION IN MDS/AML PATIENTS DEFINED BY ICC – IS AN INCLUSION INTO AML TRIALS JUSTIFIED?

HemaSphere, 2023
Sandra Huber, Constance Baer, Stephan Hutter, Frank Dicker, Manja Meggendorfer, Christian Pohlkamp, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Gregor Hoermann   +9 more
doaj   +1 more source

Primary asciminib resistance in a chronic myeloid leukemia patient with the atypical BCR::ABL1 e13a3 transcript: a case study

Haematologica
Not available.
Birte Kristin Jung, Sandra Weißmann, Caroline Schock, Manja Meggendorfer, Torsten Haferlach, Frank Dicker   +5 more
doaj   +1 more source

Human papillomavirus persistence and clearance in women living with HIV: A five‐year retrospective analysis from an Italian university center

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In women living with HIV, HPV clearance occurred after a mean of approximately 2 years under antiretroviral therapy. Baseline positivity for the high‐risk HPV pool was associated with delayed clearance, suggesting that HPV genotype may influence viral persistence more than immunovirological status in clinically stable patients.
Annunziata Carlea, Dario Colacurci, Giorgia D'Apice, Laura Letizia Mazzarelli, Massimiliano Pellicano, Luigi Falco, Ginevra Sepe, Oriana Imperatore, Giuseppe Maria Maruotti, Maurizio Guida, Laura Sarno   +10 more
wiley   +1 more source

P533: A FULLY AUTOMATED SUPERVISED AI-BASED CELL CLASSIFIER TO ACCURATELY FLAG PATHOLOGICAL SIGNATURE CELLS IN 28,285 REAL-WORLD BLOOD SMEARS

HemaSphere, 2023
Christopher Maier, Sven Maschek, Niroshan Nadarajah, Elena Müller, Martha-Lena Müller, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Christian Pohlkamp   +8 more
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source