Results 161 to 170 of about 390,769 (349)

MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells [PDF]

, 2011
Background: Our previous work and that of others strongly suggests a relationship between the infiltrative phenotype of gliomas and the expression of MMP-2.
Deepthi Are (349620), Divya Kesanakurti (222147), Jeffrey D. Klopfenstein (7925075), Aruna Venkata Badiga (7947530), Meena Gujrati (167096), Jasti S. Rao (7925081), Chandramu Chetty (200958), Dzung H. Dinh (7947392)   +7 more
core   +1 more source

A hybrid framework for lithium-ion battery SOH estimation under partial charging based on ICA reconstruction

Energy Conversion and Management: X
Accurate estimation of the State of Health (SOH) of lithium-ion batteries is essential for ensuring safety, extending service life, and enabling predictive maintenance in energy storage applications. Peak features from Incremental Capacity Analysis (ICA)
Qi Zhao, Wenbin Li, Chenye Song, Seyedmehdi Hosseininasab, Jakob Andert, Stefan Pischinger   +5 more
doaj   +1 more source

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.

Cell, 2002
B. Heissig, K. Hattori, S. Dias, M. Friedrich, B. Ferris, N. Hackett, R. Crystal, P. Besmer, D. Lyden, M. Moore, Z. Werb, S. Rafii   +11 more
semanticscholar   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

Advanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong, Haitao Wu, Weitao Wang, Xuan Zhang, Qian Chen, Yaoyu Hu, Zhengbao Zha   +6 more
wiley   +1 more source

Pathological MMP singularities as αp-quotients

Forum of Mathematics, Sigma
We construct pathological examples of MMP singularities in every positive characteristic using quotients by $\alpha _p$ -actions. In particular, we obtain non- $S_3$ terminal singularities, as well as locally stable (respectively stable ...
Quentin Posva
doaj   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Plasma Levels of Matrilysins (MMP-7 and MMP-26) and Stromelysins (MMP-3 and MMP-10) in Diagnosis of Endometrial Cancer Patients

International Journal of Molecular Sciences
Metalloproteinases (MMPs) play a significant role in cancer pathogenesis. We investigated the levels of MMP-7, MMP-26, MMP-3, and MMP-10 in comparison with the levels of a tumor marker (CA125) in the plasma of postmenopausal patients in early stages of endometrial cancer (EC) compared with control groups: patients with benign lesions (myoma uteri) and ...
Ewa Gacuta, Michał Ławicki, Monika Kulesza, Paweł Ławicki, Aleksandra Kicman, Emilia Łubińska, Sławomir Ławicki   +6 more
openaire   +3 more sources

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy

Journal of Neurochemistry, 2016
behnam vafadari, A. Salamian, L. Kaczmarek   +2 more
semanticscholar   +1 more source