Results 31 to 40 of about 396,778 (337)

28-Hydroxy-3-oxoolean-12-en-29-oic Acid, a Triterpene Acid from Celastrus Orbiculatus Extract, Inhibits the Migration and Invasion of Human Gastric Cancer Cells In Vitro

Molecules, 2019
Gastric cancer is the fifth most common tumor and has the third-highest mortality rate among various malignant tumors, and the survival rate of patients is low.
Zewen Chu, Haibo Wang, Tengyang Ni, Li Tao, Liangliang Xiang, Zhen Zhou, Yayun Qian, Masataka Sunagawa, Yanqing Liu   +8 more
doaj   +1 more source

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis. [PDF]

, 2016
The invasion-promoting MT1-MMP is a cell surface-associated collagenase with a plethora of critical cellular functions. There is a consensus that MT1-MMP is a key protease in aberrant pericellular proteolysis in migrating cancer cells and, accordingly, a
Cieplak, Piotr, Ge, Xin, Nam, Dong Hyun, Remacle, Albert G, Shiryaev, Sergey A, Strongin, Alex Y   +5 more
core   +1 more source

Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk [PDF]

Gut, 2007
The matrix metalloproteinases (MMPs) play an important role in several steps of cancer development by regulating cancer-cell growth, differentiation, apoptosis, invasion, metastasis, angiogenesis and immune surveillance.1 Several polymorphisms in the promoters of a number of MMP genes, which are thought to affect the respective MMP production in an ...
Yun, Zhai, Wei, Qiu, Xiao-Jia, Dong, Xiu-Mei, Zhang, Wei-Min, Xie, Hong-Xing, Zhang, Xiao-Yan, Yuan, Gang-Qiao, Zhou, Fu-Chu, He   +8 more
openaire   +2 more sources

The Anterior-Based Muscle-Sparing Approach for Conversion Total Hip Arthroplasty is Safe and Effective

Arthroplasty Today
Background: Total hip arthroplasty (THA) after prior hip or acetabular fracture fixation is considered higher risk than primary THA, as studies have shown reduced implant survival and higher infection rates.
Catherine M. Call, MD, Johanna Mackenzie, MPH, Zoë A. Walsh, MPH, Bailey Shevenell, BA, George Babikian, MD, Brian J. McGrory, MD, MS, Adam J. Rana, MD   +6 more
doaj   +1 more source

Chronic inflammation evoked by pathogenic stimulus during carcinogenesis

4 open, 2019
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

TNF-α Loaded on Gold Nanoparticles as a Good Therapeutic Agent against Breast Cancer AMJ13 Cells

Nano Biomedicine and Engineering, 2020
Although the remarkable anti tumor effect of tumor necrosis factor (TNF-α) and the essential role in diverse cellular and immunological properties have been evidenced, the clinical use of TNF-α is hindered due to its toxicity.
Noor Abood, Majid Jabir, Haider Kadhim
doaj   +1 more source

Who is Completing Patient-Reported Outcome Measures following Total Hip Arthroplasty? An Investigation of Completion Characteristics to Inform the Age of Mandatory Reporting Rates

Arthroplasty Today
Background: The Centers for Medicare and Medicaid Services has mandated at least 50% institutional compliance of patient-reported outcome–based performance measures (PRO-PMs) for Medicare fee-for-service patients undergoing inpatient, elective total ...
Catherine M. Call, MD, Zoë A. Walsh, MPH, Aliyah A. Olaniyan, MS, George Babikian, MD, Brian J. McGrory, MD, MS, Adam J. Rana, MD   +5 more
doaj   +1 more source

Toward Opioid-Free Total Hip Arthroplasty: A Retrospective Study of a Targeted Opioid Reduction Program in 229 Patients

Arthroplasty Today
Background: Prescription opioids leftover following arthroplasty surgery pose risks to patients and communitys. The purpose of this study was to capture opioid utilization patterns following primary total hip arthroplasty before and after a targeted ...
Mary L. Noyes, BA, Kamli N.W. Faour, BA, Zoë A. Walsh, MPH, Catherine M. Call, BA, Johanna A. Mackenzie, MPH, Adam J. Rana, MD   +5 more
doaj   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients

Bioengineering, 2020
The extracellular matrix (ECM) surrounding cancer cells becomes stiffer during tumor progression, which influences cancer cell behaviors such as invasion and proliferation through modulation of gene expression as well as remodeling of the actin ...
Wataru Sugimoto, Katsuhiko Itoh, Hiroaki Hirata, Yoshinori Abe, Takeru Torii, Yasumasa Mitsui, Yemima Budirahardja, Nobuyuki Tanaka, Keiko Kawauchi   +8 more
doaj   +1 more source