Results 21 to 30 of about 240,787 (310)

Metformin alters signaling induced crosstalk and homeostasis in the carcinogenesis paradigm “Epistemology of the origin of cancer”

4 open, 2019
The anti-hyperglycemic drug, Metformin, is effective in treating early stages of diabetes and has been associated with a 37% decrease in cancer incidence. While the precise mechanisms for the anti-cancer effects of Metformin remain to be elucidated, this
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Cyclophosphamide Exerts an Anti-Metastatic Effect by Reducing the Expression of MMP-2 and -9 in Saos-2 Osteosarcoma Cells

Ahi Evran Medical Journal, 2023
Purpose: Although osteosarcoma is the most common primary malignant bone tumor among adolescents and young adults, the molecular mechanisms underlying the development of cancer are not fully elucidated.
Gülistan Sanem SARIBAŞ
doaj   +1 more source

MMP-10 is overexpressed, proteolytically active and a potential target for therapeutic intervention in human lung carcinomas

, 2004
NoMatrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a major factor for tumor development and expansion. This study analysed MMP-10 protein expression and activity in human lung tumors of various grade, stage, and type to ...
Tijani, S., Jason H. Gill, Martin, Sandie W., Alan J. Mearns, Alan Anthoney, Mearns, A.J., Kirwan, I.G, Anikin, V.A., Anikin, V.A, Gill, J.H, Tijani, S, Loadman, Paul, Anthoney, A, Jill M. Seargent, Sandie W. Martin, Mearns, Alan J., Kirwan, Ian G., Seargent, Jill M., Anthoney, Alan, Loadman, P.M, Seargent, J.M, Mearns, A.J, Anikin, Vladimir A., Ian G. Kirwan, Tijani, Sidiq, Bibby, M.C, Martin, S.W, Sidiq Tijani, Bibby, Michael C., Loadman, Paul M., Gill, Jason H., Michael C. Bibby, Paul M. Loadman, Vladimir A. Anikin   +33 more
core   +1 more source

The Anterior-Based Muscle-Sparing Approach for Conversion Total Hip Arthroplasty is Safe and Effective

Arthroplasty Today
Background: Total hip arthroplasty (THA) after prior hip or acetabular fracture fixation is considered higher risk than primary THA, as studies have shown reduced implant survival and higher infection rates.
Catherine M. Call, MD, Johanna Mackenzie, MPH, Zoë A. Walsh, MPH, Bailey Shevenell, BA, George Babikian, MD, Brian J. McGrory, MD, MS, Adam J. Rana, MD   +6 more
doaj   +1 more source

28-Hydroxy-3-oxoolean-12-en-29-oic Acid, a Triterpene Acid from Celastrus Orbiculatus Extract, Inhibits the Migration and Invasion of Human Gastric Cancer Cells In Vitro

Molecules, 2019
Gastric cancer is the fifth most common tumor and has the third-highest mortality rate among various malignant tumors, and the survival rate of patients is low.
Zewen Chu, Haibo Wang, Tengyang Ni, Li Tao, Liangliang Xiang, Zhen Zhou, Yayun Qian, Masataka Sunagawa, Yanqing Liu   +8 more
doaj   +1 more source

MMP-1, MMP-2, MMP-7, MMP-8, MMP-10, TIMP-2, TIMP-4 levels.

, 2022
AP = acute pancreatitis. MMP = matrix metalloproteinase. TIMP = tissue inhibitor of matrix metalloproteinase.
Lindsey Hornung (5916374), Tom K. Lin (5916377), Peter R. Farrell (12085771), Hector R. Wong (8910179), Tyler Thompson (5916389), Jaimie D. Nathan (5916383), Maisam Abu-El-Haija (5916371), Patrick Lahni (516395), David S. Vitale (11748549)   +8 more
core   +1 more source

Who is Completing Patient-Reported Outcome Measures following Total Hip Arthroplasty? An Investigation of Completion Characteristics to Inform the Age of Mandatory Reporting Rates

Arthroplasty Today
Background: The Centers for Medicare and Medicaid Services has mandated at least 50% institutional compliance of patient-reported outcome–based performance measures (PRO-PMs) for Medicare fee-for-service patients undergoing inpatient, elective total ...
Catherine M. Call, MD, Zoë A. Walsh, MPH, Aliyah A. Olaniyan, MS, George Babikian, MD, Brian J. McGrory, MD, MS, Adam J. Rana, MD   +5 more
doaj   +1 more source

Chronic inflammation evoked by pathogenic stimulus during carcinogenesis

4 open, 2019
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

acdh-oeaw/mmp: v4.2

, 2023
What's Changed fix: author-keyword edges should have key, not id by @stefanprobst in https://github.com/acdh-oeaw/mmp/pull/215 Full Changelog: https://github.com/acdh-oeaw/mmp/compare/v4.1...v4.
Daniel Stoxreiter, Peter Andorfer, stefanprobst, Marc   +3 more
core   +1 more source

Toward Opioid-Free Total Hip Arthroplasty: A Retrospective Study of a Targeted Opioid Reduction Program in 229 Patients

Arthroplasty Today
Background: Prescription opioids leftover following arthroplasty surgery pose risks to patients and communitys. The purpose of this study was to capture opioid utilization patterns following primary total hip arthroplasty before and after a targeted ...
Mary L. Noyes, BA, Kamli N.W. Faour, BA, Zoë A. Walsh, MPH, Catherine M. Call, BA, Johanna A. Mackenzie, MPH, Adam J. Rana, MD   +5 more
doaj   +1 more source