Results 11 to 20 of about 390,769 (349)

In Situ Genetic Engineering Facilitates MMP-9-Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing. [PDF]

Adv Sci (Weinh)
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Zhang Y, Deng J, Cheung MY, Fu T, Qi X, Cai D, Sun J, Lu G, Shi P, Chan WY, Li X, Zhao H.   +11 more
europepmc   +2 more sources

Sodium Fluoride Inhibits MMP-2 and MMP-9 [PDF]

Journal of Dental Research, 2013
The importance of fluoride (F) in preventing dental caries by favorably interfering in the demineralization-remineralization processes is well-established, but its ability to inhibit matrix metalloproteinases (MMPs), which could also help to prevent dentin caries, has not been investigated.
Kato, MT, Bolanho, A, Zarella, BL, Salo, T, Tjaderhane, L, Buzalaf, MAR   +5 more
openaire   +2 more sources

SLAMF8 promotes the proliferation and migration of synovial fibroblasts by regulating the ERK/MMPs signalling pathway

Autoimmunity, 2022
Rheumatoid arthritis is troublesome to treat effectively and often requires concomitant long-term treatment. Meanwhile, synovial fibroblasts could induce inflammation response and lead to joint erosion, finally causing progressive joint destruction ...
Jun Liu, Ying Huang, Jiashun Zeng, Changming Chen, Peiting Li, Qiaoyi Ning, Xianyue Guan, Long Li   +7 more
doaj   +1 more source

Common Matrix Metalloproteinases (Mmp-8, -9, -25, and -26) Cannot Explain Dentigerous Cyst Expansion [PDF]

Journal of Clinical and Diagnostic Research, 2014
Objective: Mechanisms of the dentigerous cyst formation from the normal eruption follicle is unknown but disturbances in the proteolytic activity have been suspected, since the growth of these cysts is accompanied by local bone destruction.
Juho Suojanen, Niko Lehtonen, Esa Färkkilä, Jarkko Hietanen, Olli Teronen, Timo Sorsa, Jaana Hagström   +6 more
doaj   +1 more source

Control de la formación de fases en la soldadura fuerte de Al/Fe mediante haz láser Nd:YAG

Revista de Metalurgia, 2006
La reducción en el consumo de combustibles fósiles y las emergentes leyes mundiales anti-contaminación, obligan a prever una reducción en el peso de los vehículos de transporte.
L. Rodriguez, A. Mathieu, C. Langlade, A. Vannes   +3 more
doaj   +1 more source

The Effect of Two Different Botulinum Neurotoxin A On The Cortical Neuron Cells In Terms of Apoptosis and MMP 2, MMP 7, and MMP9 Localizations

Cumhuriyet Science Journal, 2023
This study aimed to associate the possible cytotoxic and apoptotic effects of Botox (Allergan) and Dysport (Ipsen) and immunolocalization of matrix metalloproteinase (MMP) proteins with HCN2 cortical neuron cell line. Accordingly, cytotoxic potentials of
Rasim Hamutoğlu, Zübeyde Akın Polat, Deniz Şahin İnan   +2 more
doaj   +1 more source

MMP-10 is overexpressed, proteolytically active and a potential target for therapeutic intervention in human lung carcinomas [PDF]

, 2004
NoMatrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a major factor for tumor development and expansion. This study analysed MMP-10 protein expression and activity in human lung tumors of various grade, stage, and type to ...
Tijani, S., Jason H. Gill, Martin, Sandie W., Alan J. Mearns, Alan Anthoney, Mearns, A.J., Kirwan, I.G, Anikin, V.A., Anikin, V.A, Gill, J.H, Tijani, S, Loadman, Paul, Anthoney, A, Jill M. Seargent, Sandie W. Martin, Mearns, Alan J., Kirwan, Ian G., Seargent, Jill M., Anthoney, Alan, Loadman, P.M, Seargent, J.M, Mearns, A.J, Anikin, Vladimir A., Ian G. Kirwan, Tijani, Sidiq, Bibby, M.C, Martin, S.W, Sidiq Tijani, Bibby, Michael C., Loadman, Paul M., Gill, Jason H., Michael C. Bibby, Paul M. Loadman, Vladimir A. Anikin   +33 more
core   +1 more source

Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms [PDF]

Royal Society Open Science, 2015
Tissue inhibitors of metalloproteinases (TIMPs) help regulate the extracellular matrix (ECM) in animals, mostly by inhibiting matrix metalloproteinases (MMPs). They are important activators of mutable collagenous tissue (MCT), which have been extensively
Ronald M. Clouse, Gregorio V. Linchangco, Alexander M. Kerr, Robert W. Reid, Daniel A. Janies   +4 more
doaj   +1 more source

Correlation between MMP-9 and extracellular cytokine HMGB1 in prediction of human ischemic stroke outcome [PDF]

, 2014
Ischemic stroke (IS) outcome predictors include clinical features, biochemical parameters and some risk factors. The relations between two main players in the ischemic brain, MMPs and HMGB1, were estimated in the plasma of ischemic stroke patients ...
Kalandadze, Iagor, Gugutsidze, Darejan, Shakarishvili, Roman, Sapojnikova, Nelly, Kartvelishvili, Tamar, Zinkevich, Vitaly, Tsiskaridze, Alexander, Asatiani, Nino   +7 more
core   +1 more source

Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances

Italian National Conference on Sensors, 2018
As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a significant protease which plays vital roles in many biological processes. MMP-9 can cleave many extracellular matrix (ECM) proteins to regulate ECM remodeling.
Hao-Hsiu Huang
semanticscholar   +1 more source