Results 31 to 40 of about 240,787 (310)

TNF-α Loaded on Gold Nanoparticles as a Good Therapeutic Agent against Breast Cancer AMJ13 Cells

open access: yesNano Biomedicine and Engineering, 2020
Although the remarkable anti tumor effect of tumor necrosis factor (TNF-α) and the essential role in diverse cellular and immunological properties have been evidenced, the clinical use of TNF-α is hindered due to its toxicity.
Noor Abood, Majid Jabir, Haider Kadhim
doaj   +1 more source

acdh-oeaw/mmp: v4.1

open access: yes, 2023
What's Changed feat: allow sorting passages by date of composition by @stefanprobst in https://github.com/acdh-oeaw/mmp/pull/214 Full Changelog: https://github.com/acdh-oeaw/mmp/compare/v4.0.1...v4.
Daniel Stoxreiter   +3 more
core   +1 more source

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas [PDF]

open access: yesWorld Journal of Surgical Oncology, 2008
AbstractBackgroundExtranodal T/NK cell lymphomas possess distinctive clinico-pathological characteristics: they are angiocentric, exhibit extensive necrosis. Prognosis is poor in the short term. The objective is to explore the expression of different MMPs in the cells and stroma which are around of the blood vessels damaged and their correlation with ...
Roa Lourdes   +5 more
openaire   +3 more sources

Fewer Pills for Fewer Problems: Strategies for Reducing Postoperative Opioid Prescribing Following Total Joint Arthroplasty

open access: yesArthroplasty Today
Opioid overprescribing is a concern within the field of arthroplasty, and a growing body of evidence suggests surgeons can prescribe smaller quantities of opioids for orthopaedic postoperative pain management without compromising patient care.
Catherine M. Call, BA   +4 more
doaj   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

open access: yes4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Epigenetic regulation of matrix metalloproteinases and their collagen substrates in cancer

open access: yesBiomolecular Concepts, 2011
Our review covers the recent epigenetic data that are focused on matrix metalloproteinases (MMPs), their inhibitors (tissue inhibitors of MMPs; TIMPs) and collagen substrates.
Chernov Andrei V., Strongin Alex Y.
doaj   +1 more source

MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients

open access: yesBioengineering, 2020
The extracellular matrix (ECM) surrounding cancer cells becomes stiffer during tumor progression, which influences cancer cell behaviors such as invasion and proliferation through modulation of gene expression as well as remodeling of the actin ...
Wataru Sugimoto   +8 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

TIMP way to stop metastasis?

open access: yesJournal of Education, Health and Sport, 2017
Matrix metalloproteinases (MMPs) are both structural and catalytic proteolytic enzymes. Many MMPs have already been described, each of which is responsible for the distribution and reconstruction of the matrix element.
Katarzyna Jarosz   +3 more
doaj   +1 more source

Hemodynamic regulation of MMP-2 and MMP-9: roles in angiogenesis and migration [PDF]

open access: yes, 2004
Hemodynamic forces generated by the flow of blood are crucial in maintaining homeostasis within the blood vessel wall. These forces, namely cyclic strain and shear stress are intricately involved in vascular remodeling, a process which underlies the ...
Von Offenberg Sweeney, Nicholas
core  

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