Results 51 to 60 of about 240,787 (310)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

acdh-oeaw/mmp: UseCase.published adde, Stelle.ort removed

, 2023
What's Changed 192 remove stelleort by @csae8092 in https://github.com/acdh-oeaw/mmp/pull/193 feat: added UseCase.published field #191 by @csae8092 in https://github.com/acdh-oeaw/mmp/pull/194 Full Changelog: https://github.com/acdh-oeaw/mmp/compare/v3.
Daniel Stoxreiter, Peter Andorfer, stefanprobst, Marc   +3 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Impact of Rurality on Total Joint Arthroplasty Access and Outcomes: A Systematic Review

Arthroplasty Today
Background: Total joint arthroplasty (TJA) is one of the most frequent orthopaedic surgeries in the United States; however, disparities in utilization and outcomes based on race, sex, and socioeconomic level have been well documented. The impact of rural
Sean L. Agrodnia, BA, Catherine M. Call, MD, Andrew D. Lachance, MD, John C. McDonald, MD, Adam J. Rana, MD, Brian J. McGrory, MD, MS   +5 more
doaj   +1 more source

The FL-MMP-2 and NTT-MMP-2 isoforms are expressed within the same tubular segments.

, 2017
Serial sections of kidneys with diabetic nephropathy were stained with PAS (A) and by immunohistochemistry for FL-MMP-2 (B) and NTT-MMP-2 (C). Staining for both isoforms is prominent within dilated tubules and occurs in the same tubular segments (arrows,
Sun Sik Bae (284124), Harin Rhee (771815), David H. Lovett (173834), Eun Young Seong (230904), Sang Soo Kim (1233510), Min Young Lee (787049), Soo Bong Lee (771821), Sang Heon Song (607351), Dong Won Lee (771820), Ihm Soo Kwak (771822), Nari Shin (3727207), Il Young Kim (771819)   +11 more
core   +1 more source

Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke [PDF]

Journal of Clinical Medicine, 2019
Ischemic stroke (IS) is multifactorial causation combining with traditional cardiovascular disease (CVD) and genetic risk factors. Combined effects of MMP-7, MMP-8 and MMP-26 on the risk of IS remain incompletely understood. We aimed to assess individual and joint effects for IS risk by weighted genetic risk score (wGRS) from these three genes and ...
Fang-I Hsieh, Hung-Yi Chiou, Chaur-Jong Hu, Jiann-Shing Jeng, Huey-Juan Lin, Jiunn-Tay Lee, Li-Ming Lien   +6 more
openaire   +2 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

MMP-8, MMP-9 and Neutrophil Elastase in Peripheral Blood and Exhaled Breath Condensate in COPD

, 2017
Chronic obstructive pulmonary disease (COPD) is characterised by progressive and irreversible airflow limitation associated with chronic inflammation involving cytokines and metalloproteinases (MMPs).
Paul S. Thomas (66668), JieHao Joshua Sng (3359384), Silvie Prazakova (3359387), Cristan Herbert (530097)   +3 more
core   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

acdh-oeaw/mmp: v3.6 better graph data

, 2023
What's Changed feature: add new api endpoint #183 by @csae8092 in https://github.com/acdh-oeaw/mmp/pull/186 minor: added changes suggest by @stefanprobst [skip ci] by @csae8092 in https://github.com/acdh-oeaw/mmp/pull/187 188 keyword graph include edge ...
Daniel Stoxreiter, Peter Andorfer, stefanprobst, Marc   +3 more
core   +1 more source